Foreword; Contents; Contributors; Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis; The Electron Transport Chain and Carcinogenesis; Respiratory Control of Redox Signaling and Cancer; Cellular Respiration and Dedifferentiation; Cellular Adaptations to Oxidative Phosphorylation Defects in Cancer; Regulation of Glucose and Energy Metabolism in Cancer Cells by Hypoxia Inducible Factor 1; The Role of Glycolysis in Cellular Immortalization; Metabolic Modulation of Carcinogenesis; Mitochondrial DNA Mutations in Tumors; Cellular Respiration and Tumor Suppressor Genes
Uncoupling Cellular Respiration: A Link to Cancer Cell Metabolism and Immune PrivilegeHow Cancer Cells Escape Death; Index
Summary
Deals with the research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This text unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer