| Description |
1 online resource (384 pages) |
| Contents |
Neurophysiology of Neuroendocrine Neurons; Contents; List of Contributors; Series Preface; Preface; About the Companion Website; SECTION 1A A Magnocellular Neuroendocrine Neurons: Properties and Control of Vasopressin and Oxytocin Neurons; 1 Electrophysiology of Magnocellular Neurons In Vivo; 1.1 Introduction; 1.2 Opening the window on the brain; 1.3 The milk-ejection reflex; 1.3.1 Vasopressin cells and phasic firing; 1.4 Osmotic responses; 1.5 Responses to other stimuli; 1.6 The future; 1.7 Technical appendix; 1.7.1 The milk ejection preparation: Technical details |
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1.7.2 Ventral surgery: Technical details1.7.3 Recording electrodes; 1.7.4 Analysis of firing patterns; Cited references; 2 Oxytocin Neurons during Suckling: Lessons from Organotypic Cultures; 2.1 Introduction; 2.2 Hypothalamic slices in vitro: acute slices versus organotypic cultures; 2.2.1 Acute slices; 2.2.2 Organotypic slice cultures; 2.3 Magnocellular neurons in hypothalamic organotypic slice cultures; 2.3.1 Basic electrophysiological properties of OT neurons; 2.3.2 Synaptic activity; 2.3.3 OT neurons in culture display rhythmic HFDs of action potentials |
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2.3.4 Synchronization of rhythmic HFDs of action potentials2.3.5 The effect of OT on OT neurons; 2.3.6 OT increases GABAergic IPSPs/IPSCs through a presynaptic mechanism; 2.4 Perspectives; 2.4.1 Organotypic slice cultures as a model to study OT neurons; 2.4.2 Intrinsic versus synaptic control in OT neurons; 2.4.3 An intrahypothalamic autonomous burst generator; 2.4.4 Higher organization of the burst generator; 2.4.5 A few riddles with organotypic cultures; 2.4.6 Questions with other in vitro models; Cited references |
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3 Peptidergic Control of Oxytocin and Vasopressin Neurons and Its Role in Reproductive and Hypertension-Associated Plasticity3.1 Introduction; 3.1.1 Oxytocin, birth and lactation; 3.1.2 Vasopressin and blood pressure control; 3.1.3 The magnocellular neurosecretory system; 3.2 Electrical activity of magnocellular neurosecretory cells; 3.3 In vivo electrophysiological recording from magnocellular neurosecretory cells; 3.3.1 Transpharyngeal surgery for exposure of the supraoptic nucleus; 3.3.2 Electrical recording of action potential discharge; 3.3.3 Antidromic identification of recorded neurons |
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3.4 Plasticity in vasopressin neuron activity during the development of hypertension3.5 Plasticity in afferent input excitation of oxytocin neurons in pregnancy and lactation; 3.6 Perspectives; Cited references; 4 The Osmotic Control of Vasopressin-Releasing Neurons; 4.1 Introduction: Basis of osmoregulation; 4.1.1 Importance of electrolyte and osmotic homeostasis; 4.1.2 Osmotic stress; 4.1.3 Cell volume regulation; 4.1.4 Systemic osmoregulation; 4.1.5 The hypothalamo-neurohypophysial vasopressin system; 4.1.6 Osmotic control of vasopressin involves an array of mechanisms |
| Summary |
Neurophysiology of Neuroendocrine Neurons provides researchers and students with not only an understanding of neuroendocrine cell electrophysiology, but also an appreciation of how this model system affords access to virtually all parts of the neuron for detailed study - something unique compared to most types of neuron in the brain. Chapters range from those describing the rich history and current state of in vivo recordings, highlighting the precise relationship between the patterns of action potential discharge in these neurons and hormone release, to in vitro approaches where neuroendocrin |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Neurons -- Physiology.
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Neuroendocrine Cells -- physiology
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Neurons -- physiology
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Neurosecretory Systems -- physiology
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Neurons -- Physiology
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| Form |
Electronic book
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| Author |
Armstrong, William E., editor
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Tasker, Jeffrey G., editor
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| ISBN |
9781118606797 |
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1118606795 |
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1118606817 |
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9781118606810 |
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9781118965115 |
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1118965116 |
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9781322212845 |
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1322212848 |
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