| Description |
1 online resource (ix, 199 pages) : illustrations |
| Series |
Progress in inflammation research |
|
PIR (Series)
|
| Contents |
Voltage-gated sodium channels and pain associated with nerve injury and neuropathies / Joel Black, Bryan Hains, Sulayman Dib-Hajj and Stephen Waxman -- Current approaches for the discovery of novel NaV channel inhibitors for the treatment of brain disorders / Jeffrey J. Clare -- Voltage-gated sodium channels and visceral pain / Jennifer Laird, Fernando Cervero and Jennifer Laird -- The functional interaction of accessory proteins and voltage-gated sodium channels / Kenji Okuse and Mark Baker -- Sodium channels and nociceptive nerve endings / James Brock -- Signalling cascades that modulate the activity of sodium channels in sensory neurons / Grant D. Nicol -- NaV1.8 as a drug target for pain / Lodewijk Dekker and David Cronk -- Role of voltage-gated sodium channels in oral and craniofacial pain / Michael S. Gold -- Sodium channel gating and drug blockade / Andreas Scholz -- Future directions in sodium channel research / John N. Wood |
| Summary |
Discussing pharmacological approaches to the drug targeting of sodium channels, this book focuses on Nav1.8. It also highlights the functional diversity of sodium channels in part provided by post-transcriptional processing and the insights into sodium channel function that are provided by tissue specific and inducible gene knock-out technology |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Pain.
|
|
Sodium channels.
|
|
Analgesics.
|
|
Pain
|
|
Sodium Channels
|
|
Analgesics
|
|
HEALTH & FITNESS -- Pain Management.
|
|
MEDICAL -- Pain Medicine.
|
|
Analgesics
|
|
Pain
|
|
Sodium channels
|
|
Analgesie.
|
|
Natrium.
|
|
Ionenkanalen.
|
|
Natriumkanal -- Schmerztherapie.
|
|
Schmerztherapie -- Natriumkanal.
|
| Form |
Electronic book
|
| Author |
Coward, Kevin, 1969-
|
|
Baker, Mark D., 1960-
|
| ISBN |
9783764374112 |
|
376437411X |
|
9783764370626 |
|
3764370629 |
|
1281349208 |
|
9781281349200 |
|
9786611349202 |
|
6611349200 |
|
