| Description |
1 online resource (x, 325 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; 1551 |
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Springer protocols |
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Methods in molecular biology (Clifton, N.J.) ; v. 1551
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|
Springer protocols (Series)
|
| Contents |
Haplotyping of heterozygous SNPs in genomic DNA using long-range PCR / Barbara Arbeithuber, Angelika Heissl, and Irene Tiemann-Boege -- Quantification and sequencing of crossover recombinant molecules from Arabidopsis pollen DNA / Kyuha Choi, Nataliya E. Yelina, Heïdi Serra, and Ian R. Henderson -- PacBio for haplotyping in gene families / Wei Zhang and Joachim Messing -- High molecular weight DNA enrichment with peptide nucleic acid probes / Nicholas M. Murphy, Colin W. Pouton, and Helen R. Irving -- High-throughput sequencing of the major histocompatibility complex following targeted sequence capture / Johannes Pröll, Carina Fischer, Gabriele Michelitsch, Martin Danzer, and Norbert Niklas -- Pedigree-defined haplotypes and their applications to genetic studies / Chester A. Alper and Charles E. Larsen -- Haplotyping a non-meiotic diploid fungal pathogen using induced aneuploidies and SNP/CGH microarray analysis / Judith Berman and Anja Forche -- Whole-genome haplotyping of single sperm of Daphnia pulex (crustacea, anomopoda) / Sen Xu and Kim Young -- Chromosome-range whole-genome high-throughput experimental haplotyping by single-chromosome microdissection / Li Ma, Wenzhi Li, and Qing Song -- Phased genome sequencing through chromosome sorting / Xi Chen, Hong Yang, and Wing Hung Wong -- Long fragment read (LFR) technology : cost-effective, high-quality genome-wide molecular haplotyping / Mark A. McElwain, Rebecca Yu Zhang, Radoje Drmanac, and Brock A. Peters -- Contiguity-preserving transposition sequencing (CPT-Seq) for genome-wide haplotyping, assembly, and single-cell ATAC-Seq / Lena Christiansen, Sasan Amini, Fan Zhang, Mostafa Ronaghi, Kevin L. Gunderson, and Frank J. Steemers -- Fosmid pool-based next generation sequencing approach to haplotype-resolve whole genomes / Eun-Kyung Suk, Sabrina Schulz, Birgit Mentrup, Thomas Huebsch, Jorge Duitama, and Margret R. Hoehe -- Discovery of rare haplotypes by typing millions of single-molecules with bead emulsion haplotyping (BEH) / Elisabeth Palzenberger, Ronja Reinhardt, Leila Muresan, Barbara Palaoro, and Irene Tiemann-Boege -- Computational haplotype inference from pooled samples / Quan Long |
| Summary |
This volume details protocols for genetic, molecular, cytological, and bioinformatic methods for determining haplotypes. Haplotyping: Methods and Protocols guides readers through methods that directly type haploid cells, difficult-to-resolve gene families, high-resolution, short range haplotyping for targeted loci, and long-range haplotyping for whole chromosomes or genomes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical Haplotyping: Methods and Protocols, aims to provide researchers with an overview of experimental methods for haplotyping |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerProtocol, viewed February 1, 2017) |
| Subject |
Genetics -- Laboratory manuals
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Variation (Biology) -- Laboratory manuals
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Haploidy.
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Haploidy
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Haplotypes
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Medical genetics.
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Medical -- Genetics.
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Haploidy
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Genetics
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Variation (Biology)
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Tiemann-Boege, Irene, editor
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Betancourt, Andrea, editor
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| ISBN |
9781493967506 |
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1493967509 |
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1493967487 |
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9781493967483 |
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