| Description |
1 online resource |
| Series |
Pharmacology-research, safety testing and regulation |
|
Pharmacology-research, safety testing, and regulation series.
|
| Contents |
""VINCRISTINE: CLINICAL USES, PHARMACOKINETICS AND IMPACTS ON HEALTH""; ""VINCRISTINE: CLINICAL USES, PHARMACOKINETICS AND IMPACTS ON HEALTH""; ""Library of Congress Cataloging-in-Publication Data""; ""Contents""; ""Preface""; ""Chapter 1: Vincristine as an Inductor of Drug Resistance Marker Expression in Neoplastic Cells""; ""Abstract""; ""Biochemical Characterization of P-Glycoprotein and Multidrug Resistance Associated Proteins""; ""Vincristine As Inductor of P-gp and MRPs � Insight to Drug Sensitivity of Cells"" |
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""Cellular Modification of Vincristine and Vincristine-Induced Free Radical Formation � Insight into the Drug Sensitivity of Cells""""Effects of Vincristine on Cell Signalization � Insight to the Drug Sensitivity of Cells""; ""Conclusion""; ""Acknowledgments""; ""References""; ""Chapter 2: Clinical Utility of Vincristine in the Treatment of Human Carcinomas""; ""Abstract""; ""Introduction""; ""History of Vincristine""; ""Molecular Characteristics of Vincristine""; ""Clinical Pharmacology of Vincristine""; ""Clinical Use of Vincristine""; ""Vincristine Toxicity""; ""Conclusion"" |
| Summary |
Vincristine is a naturally occurring alkaloid isolated from the leaves of the plant Catharanthus roseus. It has a wide range of clinical applications. Extracts of the plant have found application in wound healing, in the treatment of diabetic ulcers and diabetes mellitus, and in cancer chemotherapy. In this book, the authors discuss the clinical uses, pharmacokinetics and impacts on health of Vincristine. Topics discussed include Vincristine as an inductor of drug resistance marker expression in neoplastic cells; clinical utility of Vincristine in the treatment of human carcinomas; inadvertent |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Description based on print version record |
| Subject |
Alkaloids -- Therapeutic use.
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Vincristine.
|
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Vincristine
|
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SCIENCE -- Life Sciences -- Biochemistry.
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Alkaloids -- Therapeutic use
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Vincristine
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| Form |
Electronic book
|
| Author |
Coello, Juan M., editor
|
|
Sabres, Yolanda D., editor
|
| LC no. |
2020687879 |
| ISBN |
9781628088878 |
|
1628088877 |
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