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Title Neuroendocrine tumors : review of pathology, molecular and therapeutic advances / Aejaz Nasir, Domenico Coppola, editors
Published New York : Springer, 2016
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Description 1 online resource (xiii, 543 pages)
Contents Preface; Contents; Part I: General Topics in Neuroendocrine Tumor Pathology; Neuroendocrine Tumor Classification Systems: Grading; General; Embryologic Classification of NENs [2]; Anatomic Distribution of NENs [3-5]; Inherited Conditions; Differentiation [6-8]; Grading; Stomach [3, 14]; Pancreas; Jejunum, Ileum, Appendix, and Cecum (Midgut NETs); Distal Colon and Rectum (Hindgut); Lung and Thymus (Thorax, Foregut) [28]; Pheochromocytoma, Paraganglioma, and Medullary Thyroid Cancer [24, 29]; Pheochromocytomas; Medullary Thyroid Cancer (MTC); C Cell Hyperplasia
Anterior Pituitary Functional Classification of Pituitary Adenomas; WHO Classification of Pituitary Tumors; Radiologic Classification of Pituitary Tumors; References; Neuroendocrine Tumor Classification Systems: Staging; General [1, 2]; ENETS System for Classification of NETs [1, 2]; UICC/AJCC System for Classification of NETs [5]; AJCC System for Classification of NETs; References; Differential Diagnosis of Neuroendocrine Tumors; Introduction; Neuroendocrine Tumor Versus Adenocarcinoma; Neuroendocrine Tumors Versus Primary Tumors Originated in the Liver
Neuroendocrine Tumors Versus Other Neoplasms Neuroendocrine Tumors Versus Solid Pseudopapillary Neoplasm (SPN) of the Pancreas; Neuroendocrine Tumors Versus Paragangliomas; Neuroendocrine Tumors Versus Nonepithelial Neoplasms; Determination of Origin for Metastatic NET; Neuroendocrine Tumors Versus Prostate Cancer; References; Role of Immunohistochemistry and Molecular Genetics in Neuroendocrine Tumors; Introduction; Immunophenotypical Profiles of Neuroendocrine Tumors; Immunohistochemical Markers of Epithelial Differentiation and Neuroendocrine Tumors
Immunohistochemical Markers of Neuroendocrine Differentiation Immunohistochemistry for Secretory Proteins and Receptors; Location of Neuroendocrine Neoplasms and Choice of Immunohistochemical Markers; Epithelial Versus Site-specific Immunohistochemical Markers; Immunohistochemistry and Grade of Neuroendocrine Neoplasms; Role of Immunohistochemistry in Differentiating Neuroendocrine from Other Malignancies; Molecular Genetics of Neuroendocrine Tumors; References; Gastroenteropancreatic: Poorly Differentiated Neuroendocrine Carcinoma; Introduction; Epidemiology; Molecular Pathology
Histopathologic Classification Schemes Histologic Subtypes of PDNEC; Small Cell Carcinoma (SCC); Large Cell Carcinoma (LCC); Mixed Adenoneuroendocrine Carcinoma (MANEC); Site-Specific PD-NECs; Esophageal Poorly Differentiated NEC (PD-NEC); Gastric PD-NEC; PD-NEC of the Colon and Rectum; Histopathologic Findings; Pancreatic PD-NEC; Clinical Features of PD-NEC; Role of Immunohistochemistry in PD-NEC; Neuroendocrine and Other IHC Markers; Synaptophysin (Syn); Chromogranin A (CgA); Neuron-Specific Enolase (NSE); CD56; CAM 5.2; CDX2; CEA; TTF-1; ASH1; P53
Summary This comprehensive subspecialty reference book on NeuroEndocrine Tumor (NET) pathology brings together the diagnostic and clinical expertise of an outstanding team of practicing neuroendocrine pathologists and oncologists. In addition to in-depth coverage of clinico-pathologic aspects of NETs of the various organ systems, the recent histological grading and staging schemes proposed by the North American and European NeuroEndocrine Tumor Societies (NANETS, ENETS), the World Health Organization (WHO) and the American Joint Committee on Cancer (AJCC), this book also focuses on the recent molecular and therapeutic advances in the field of NET pathology and oncology. Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances will be an essential reference book for anatomic pathology (histopathology) residents, fellows, surgical pathologists, researchers, oncologists, surgeons and other medical professionals practicing advanced NET Pathology and Oncology in academia, community, private practice and research settings
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Neuroendocrine tumors.
Endocrine glands -- Tumors.
Neuroendocrine Tumors -- pathology.
Neuroendocrine Tumors -- metabolism.
Neuroendocrine Tumors -- therapy.
Form Electronic book
Author Nasir, Aejaz, editor
Coppola, Domenico (Physician), editor
ISBN 9781493934263 (electronic bk.)
1493934260 (electronic bk.)