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Book
Author Wright, Denis Matthew John

Title Potential antiarrhythmic and cardioprotective agents based on adenosine / by Denis Matthew John Wright
Published [Place of publication not identified] : [publisher not identified], 1998

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Location Call no. Vol. Availability
 W'PONDS  572.425 Wri/Paa  AVAILABLE
Description viii, 171 leaves : illustrations ; 30 cm
Summary Adenosine is an endogenous ligand which is involved in a large number of physiological processes. Intravenous treatment of animals with adenoisine, which is quickly metabolised, has the effect of temporarily lowering the heart-rate. Several highly potent compounds more resistent to metabolic degradation were synthesised. The second part of the project involved synthesis of compounds which were hopefully selective for the A3 adenoisine receptor which has the most limited tissue distribution within the body and is thought to be involved in a number of pathological processes including asthma
Notes Submitted to the School of Biological and Chemical Sciences of the Faculty of Science and Technology, Deakin University
Thesis (Ph.D.)--Deakin University, Victoria, 1998
Bibliography Bibliography: leaves 159-171
Subject Adenosine -- Metabolism.
Adenosine -- Receptors.
Genre/Form Academic theses.
Author Deakin University. Faculty of Science and Technology.
Deakin University. School of Biological and Chemical Sciences