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Book Cover
Author Rouault, Tracey A.

Title Iron-Sulfur Clusters in Chemistry and Biology
Published Berlin : De Gruyter, 2014
Online access available from:
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Description 1 online resource (672 pages)
Contents History of iron sulfur cluster protein research / Bonomi and Rouault -- Chemistry of iron sulfur clusters / Ichiye -- Spectroscopic methods to use in characterization of FeS proteins -- EPR / Hendrich -- Mossbauer spectroscopy an evaluation of FeS clusters : explanation of the technique / Lindahl and Chakrabarti -- Nitrogenase : role of the molybenum cofactor and the carbide in capturing nitrogen / Ribbe and Hu -- Structure of nitrogenase MoFe / Einsle -- Biotin synthase : role of the FeS cluster / Jarrett -- Aerobic Co dehydrogenase : a Mo, Cu, and FeS containing enzyme / Hille -- Radical SAM chemistry and FeS / Booker -- Iron-sulfur clusters and molecular oxygen : function, adaptation, degradation, and repair / Nicolet and Fontecilla -- Model organisms for study of FeS : discovery of bacterial proteins dedicated to stepwise synthesis of iron sulfur clusters / Dos Santos and Dennis Dean -- A stress responsive FeS synthesis system in bacteria : the Suf operon / W. Outten -- FeS clusters in bacterial regulation / Kiley and Mettert -- FeS assembly in gram positive bacteria / Dos Santos -- FeS assembly and regulation in yeast, including relationship between FeS biogenesis and mitochondrial iron overload / Dancis -- Regulation of yeast iron homeostasis, and the role of FeS clusters in regulation of the iron regulon / C. Outten -- The mammalian FeS switch of iron regulatory protein 1 / Rouault -- FeS biogenesis and human diseases / Tong -- The connection between mammalian molybdenum cofactor and FeS clusters synthesis / Leimkuhler -- Iron-sulphur proteins and genome stability / Gari -- DNA repair and iron-sulfur cluster assembly / Lill and Wohlschlegel -- Plant FeS biogenesis / Hong -- The FeS origin of life theory / Peters and Boyd
Summary This volume on iron-sulfur clusters includes chapters that cover the history of the discovery of iron-sulfur clusters in the 1960s to discoveries of their role in the enzyme, aconitase (1980s), and numerous other proteins. It explains basic chemistry principles, how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of FeS proteins
Bibliography Includes bibliographical references and index
Notes In English
Print version record
Subject Iron-Sulfur Proteins.
Iron-sulfur proteins.
Form Electronic book
Author Adams, Michael W. W., 1954-
Andrade, Susana L. A
Bonomi, Francesco.
Booker, Squire
Boyd, Eric S
Broderick, Joan B
Chakrabarti, Mrinmoy
Dancis, Andy
Dean, Dennis.
Dos Santos, Patricia
Einsle, Oliver
Fontecilla, Juan
Gari, Kerstin
Hendrich, Michael
Hille, Russ.
Hu, Yilin
Ichiye, Toshiko
Jarrett, Joe
Kiley, Patricia
Lanz, Nicholas D
Leimkuhler, Silke
Lill, Roland.
Lindahl, Paul
Mettert, Erin L
Nicolet, Yvain.
Outten, Caryn
Outten, Wayne
Pain, Debkumar
Perna, Nicole T
Petasis, Doros T
Peters, John.
Ribbe, Markus
Schut, Gerrit J
Shepard, Eric M
Spatzal, Thomas
Tong, Wing Hang
Uzarska, Marta
Wohlschlegel, James
Ye, Hong.
ISBN 3110308436 (electronic bk.)
9783110308433 (electronic bk.)