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Book Cover
E-book

Title Experimental and applied immunotherapy / Jeffrey Medin, Daniel Fowler, editors
Published New York : Humana Press, ©2011

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Description 1 online resource (xvii, 442 pages) : illustrations (some color)
Contents T cell therapy: state-of-the-art -- Extending the use of adoptive T cell immunotherapy for infections and cancer -- Non-T cell therapeutic approaches -- B lymphocytes in cancer immunology -- Monoclonal antibody therapy for cancer -- Natural killer cells for cancer immunotherapy -- Dendritic cell-based cancer vaccines: practical considerations -- Mesenchymal stromal cells: an emerging cell-based pharmaceutical -- T cell therapeutic approaches -- Tumor-specific mutations as targets for cancer immunotherapy -- Counteracting subversion of MHC class II antigen presentation by tumors -- Mechanisms and implications of immunodominance in CD8 T-cell responses -- T regulatory cells and cancer immunotherapy -- Negative regulators in cancer immunology and immunotherapy -- Genetically engineered antigen specificity in T cells for adoptive immunotherapy -- Non-cellular aspects of cancer immunotherapy -- Cytokine immunotherapy -- Transcriptional modulation using histone deacetylase inhibitors for cancer immunotherapy -- Combining cancer vaccines with conventional therapies -- Combining oncolytic viruses with cancer immunotherapy -- Radiation therapy and cancer treatment: from the basics to combination therapies that ignite immunity -- Assessing immunotherapy through cellular and molecular imaging -- Transplantation -- Allogeneic and autologous transplantation therapy of cancer: converging themes
Summary Immunotherapy is now recognized as an essential component of treatment for a wide variety of cancers. It is an interdisciplinary field that is critically dependent upon an improved understanding of a vast network of cross-regulatory cellular populations and a diversity of molecular effectors; it is a leading example of translational medicine with a favorable concept-to-clinical-trial timeframe of just a few years. There are many established immunotherapies already in existence, but there are exciting new cancer immunotherapies just on the horizon, which are likely to be more potent, less toxic
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Immunotherapy.
Immunotherapy -- methods
Neoplasms -- therapy
Cancer Vaccines -- therapeutic use
Neoplasms -- immunology
T-Lymphocytes -- immunology
Immunotherapy
HEALTH & FITNESS -- Diseases -- Cancer.
MEDICAL -- Oncology.
Immunotherapy
Form Electronic book
Author Medin, Jeffrey.
Fowler, Daniel H.
ISBN 9781607619802
1607619806