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Title Liver immunology : principles and practice / M. Eric Gershwin, John M. Vierling and Michael P. Manns, editors
Edition Second edition
Published New York : Humana Press, [2013]
©2014
Table of Contents
1.Introduction / Ian R. Mackay1
2.Core Concepts in Immunology / Derek Doherty11
3.The Geoepidemiology of Autoimmune Liver Disease / Renqian Zhong27
4.Diagnostic Liver Immunology / Christopher L. Bowlus45
5.The Liver as a Lymphoid Organ / Percy A. Knolle55
6.Innate Immunity and Disorders of the Liver / Ulrike Protzer65
7.The Liver and Immune Tolerance / Zhe-Xiong Lian79
8.The Diagnosis and Classification of Immune-Mediated Hepatic Diseases / Fernando Alvarez95
9.The Diagnosis and Classification of Immune-Mediated Biliary Diseases / Gideon M. Hirschfield111
10.Bacterial Infections in Liver / M. Eric Gershwin123
11.The Diagnosis and Classification of Parasitic Diseases of the Liver / Manisha Mandal145
12.Viral Diseases of the Liver / Yaron Dan159
13.Hepatitis A: Immune Response and Virus Evolution / Gerardo Kaplan173
14.Immunopathogenesis of Chronic Hepatitis B and the Clinical Events That Shape its Natural History / Robert P. Perrillo191
15.Hepatitis C / Francesco Negro207
16.Immunopathogenesis of Hepatitis D / Heiner Wedemeyer231
17.Hepatitis E / Mikio Zeniya243
18.Primary Biliary Cirrhosis / M. Eric Gershwin253
19.Autoimmune Hepatitis / Giorgina Mieli-Vergani281
20.Primary Sclerosing Cholangitis (PSC) / Michael Trauner301
21.Overlap Syndromes / Kirsten Muri Boberg317
22.Alcoholic Liver Disease / Gyongyi Szabo331
23.Nonalcoholic Fatty Liver Disease / Arun J. Sanyal345
24.Paediatric Liver Disease / Diego Vergani361
25.Mechanisms of Acute Liver Failure / Alexander Koch373
26.Nonimmune-Mediated Drug-Induced Hepatotoxicity / Christian P. Strassburg389
27.Immune-Mediated Drug-Induced Liver Injury / Guruprasad P. Aithal401
28.The Immunopathogenesis of Cirrhosis / Wajahat Z. Mehal413
29.Graft-Versus-Host Disease / John M. Vierling425
30.Immune-Mediated Liver Disease in the Transplanted Liver / James Neuberger443
31.The Future of Liver Immunology / Michael P. Manns463
 Index471
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Description 1 online resource (xvi, 480 pages) : illustrations (some color)
Contents Introduction / Ian R. Mackay -- Core Concepts in Immunology / Cliona O'Farrelly and Derek Doherty -- The Geoepidemiology of Autoimmune Liver Disease / Carlo Selmi, Cecilia B. Chighizola, Angela Ceribelli, Maria De Santis [and 2 others] -- Diagnostic Liver Immunology / Christopher L. Bowlus -- The Liver as a Lymphoid Organ / Percy A. Knolle -- Innate Immunity and Disorders of the Liver / Mathias Heikenwalder, Percy Knolle and Ulrike Protzer -- The Liver and Immune Tolerance / Zhigang Tian, Cai Zhang and Zhe-Xiong Lian -- The Diagnosis and Classification of Immune-Mediated Hepatic Diseases / Fernando Alvarez -- The Diagnosis and Classification of Immune-Mediated Biliary Diseases / Gideon M. Hirschfield and B. Chir. -- Bacterial Infections in Liver / Eirini I. Rigopoulou, Daniel S. Smyk, Timoklia Orfanidou [and 2 others] -- The Diagnosis and Classification of Parasitic Diseases of the Liver / Shyamapada Mandal and Manisha Mandal -- Viral Diseases of the Liver / Gadi Lalazar and Yaron Ilan -- Hepatitis A: Immune Response and Virus Evolution / Rosa M. Pintó, Albert Bosch and Gerardo Kaplan -- Immunopathogenesis of Chronic Hepatitis B and the Clinical Events That Shape its Natural History / Stevan A. Gonzalez and Robert P. Perrillo -- Hepatitis C / Mario U. Mondelli, Stefania Varchetta and Francesco Negro -- Immunopathogenesis of Hepatitis D / Sebastian Lunemann, Jan Grabowski and Heiner Wedemeyer -- Hepatitis E / Hiroki Takahashi and Mikio Zeniya -- Primary Biliary Cirrhosis / Pietro Invernizzi, Patrick S.C. Leung, Xiong Ma and M. Eric Gershwin -- Autoimmune Hepatitis / Diego Vergani, Rodrigo Liberal and Giorgina Mieli-Vergani -- Primary Sclerosing Cholangitis / Harald Hofer, Emina Halilbasic, Katharina Staufer and Michael Trauner -- Overlap Syndromes / Said Al Mamari, Roger W. Chapman and Kirsten Muri Boberg -- Alcoholic Liver Disease / Gyongyi Szabo -- Nonalcoholic Fatty Liver Disease / Vaishali Patel and Arun J. Sanyal -- Paediatric Liver Disease / Giorgina Mieli-Vergani, Rodrigo Liberal and Diego Vergani -- Mechanisms of Acute Liver Failure / Christian Trautwein and Alexander Koch -- Nonimmune-Mediated Drug-Induced Hepatotoxicity / Christian P. Strassburg -- Immune-Mediated Drug-Induced Liver Injury / Einar S. Björnsson and Guruprasad P. Aithal -- The Immunopathogenesis of Cirrhosis / Bin Gao, Scott L. Friedman and Wajahat Z. Mehal -- Graft-Versus-Host Disease / Ali Raza and John M. Vierling -- Immune-Mediated Liver Disease in the Transplanted Liver / Palak Jitendrakumar Trivedi, Ka-Kit Li and James Neuberger -- The Future of Liver Immunology / M. Eric Gershwin, John M. Vierling and Michael P. Manns
Core Concepts in Immunology -- The Geoepidemiology of Autoimmune Liver Disease -- Diagnostic Liver Immunology -- The Liver as a Lymphoid Organ -- Innate Immunity and Disorders of the Liver -- The Liver and Immune Tolerance -- The Diagnosis and Classification of Immune-Mediated Hepatic Diseases -- The Diagnosis and Classification of Immune-Mediated Biliary Diseases -- Bacterial Infections in Liver -- The Diagnosis and Classification of Parasitic Diseases of the Liver -- The Diagnosis and Classification of Parasitic Diseases of the Liver -- Viral Diseases of the Liver -- Hepatitis A: Immune Response and Virus Evolution -- Immunopathogenesis of Chronic Hepatitis B and the Clinical Events That Shape its Natural History -- Hepatitis C -- Immunopathogenesis of Hepatitis D -- Hepatitis E -- Primary Biliary Cirrhosis -- Autoimmune Hepatitis -- Primary Sclerosing Cholangitis (PSC) -- Overlap Syndromes -- Alcoholic Liver Disease -- Nonalcoholic Fatty Liver Disease -- Paediatric Liver Disease -- Mechanisms of Acute Liver Failure -- Nonimmune-Mediated Drug-Induced Hepatotoxicity -- Immune-Mediated Drug-Induced Liver Injury -- The Immunopathogenesis of Cirrhosis -- Graft-Versus-Host Disease -- Immune-Mediated Liver Disease in the Transplanted Liver -- The Future of Liver Immunology
Summary Liver Immunology: Principles and Practice, Second Editionbegins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters thatprovide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediatedliver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Editionwill again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed Dec. 3, 2013)
In Springer e-books
Subject Liver -- Diseases -- Immunological aspects.
Liver -- Immunology.
Form Electronic book
Author Gershwin, M. Eric, 1946- editor
Vierling, John M., editor
Manns, Michael P. (Michael Peter), editor
ISBN 9783319020969 (electronic bk.)
331902096X (electronic bk.)
3319020951
9783319020952