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Title Functionalized smart nanomaterials for point-of-care testing / Amit Kumar Mandal, Suvankar Ghorai, Azamal Husen, editors
Published Singapore : Springer, 2023

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Description 1 online resource (260 p.)
Series Smart Nanomaterials Technology
Smart Nanomaterials Technology
Contents Intro -- Preface -- About This Book -- Contents -- About the Editors -- Overview of the Current Nano-Materials, Synthesis, Properties and Characterization -- 1 Introduction -- 2 Metal-Based Nanoparticles -- 3 Quantum Dots -- 4 Metal-Organic Frameworks (MOFs) -- 5 Carbon Nanotubes -- 6 Nanoshells -- 7 Nanogels -- 7.1 Classification of Nanogels -- 8 Nanofibers -- 9 Flexible Hybrid Composites -- 10 Conclusion and Future Aspects -- References -- Nanoinformatics Applied to Smart Nanomaterials -- 1 Introduction
2 An Overview of Nanoinformatics in the Context of Nanomedicine and the Development of Smart Nanomaterials -- 3 The Application of Smart Nanomaterials for Drug Delivery -- 4 Design of Smart Nanomaterials for Drug Delivery Using Nanoinformatics -- 5 The Existing Smart Nanomaterials for Drug Delivery -- 6 Conclusion -- References -- Nanomaterials in Lateral Flow Assay -- 1 Introduction -- 2 Nanomaterials -- 2.1 AuNPs -- 2.2 Carbon-Based Nanomaterials -- 2.3 Quantum Dots (QDs) -- 2.4 Magnetic Nanoparticles (MNPs) -- 2.5 Nanoenzymes -- 2.6 Other Nanoparticles -- 3 Conclusion -- References
Aptamer-Based Lateral Flow Assay as a Smart Point-of-Care Devices -- 1 Introduction -- 2 Aptamers in Developing LFA -- 3 Flexible LFA Design -- 4 Multiplex LFA -- 5 Different Formats of Aptamer-Based LFA -- 5.1 Sandwich Aptamer-Based LFA -- 5.2 Competitive Aptamer-Based LFA -- 6 Interpretation of the Results -- 7 Applications of Aptamer-Based LFA -- 8 Conclusion -- References -- CRISPR-Based Point-of-Care Testing (POCT) Devices for Detection of Opportunistic Pathogens -- 1 Introduction -- 2 CRISPR-Based POCT Detection on Opportunistic Bacteria
3 Detection of Opportunistic Protozoa by CRISPR-Based POCT -- 4 Detection by CRISPR-Based POCT on Opportunistic Fungus -- 5 Detection of Virus by CRISPR-Based POCT -- 6 Conclusion -- References -- Microfluidic Chips as Point-of-Care Testing for Develop Diagnostic Microdevices -- 1 Introduction -- 2 Microfluidic Tests -- 2.1 Introduction -- 2.2 Benefits of Microfluidic Tests in Clinic Laboratory -- 2.3 Equipment Varieties for Microfluidic Tests -- 3 Microfluidic Tests for POC Diagnosis of Infectious Diseases -- 3.1 Introduction -- 3.2 Applications for Diagnosis of Infectious Diseases
4 Microfluidic Tests for POC Diagnosis of CVDs -- 4.1 Introduction -- 4.2 Applications for Diagnosis of CVDs -- 5 Microfluidic Tests for POC Diagnosis of Tumors -- 5.1 Introduction -- 5.2 Applications for Diagnosis of Cancer -- 6 Conclusions and Prospects -- References -- Magnetic-Nanosensor-Based Diagnostic Chips: An Overview -- 1 Introduction -- 2 Type of Magnetic-Nanosensor-Based Diagnostic Chips -- 3 Characterisation Techniques -- 4 Physical and Chemical Characteristics of Magnetic-Nanosensor-Based Diagnostic Chips -- 5 Application and Impact of Magnetic-Nanosensor-Based Diagnostic Chips
Summary This book highlights the recent advancement in point-of-care testing (POCT) technologies utilizing smart nanomaterials for the analysis of biomarkers related to disease, which includes metabolites, enzymes, proteins, nucleic acids, cancer cells and multidrug-resistant pathogen. The POCT refers to medical diagnostic tests performed near the place and time of patient care. During the recent pandemic of COVID-19, many realized the importance of affordable, rapid and accurate POCT devices and their usefulness to combat the spread of the infection. The chapters in this book describe the emergence of smart nanomaterials with unique physical and chemical properties being utilized in POCT devices for immobilizing biorecognition elements and labels for signal generation, transduction and amplification. It showcases the applications of these smart nanomaterials and their superiority in developing point-of-care diagnostics devices in a wide range of applied fields like food industry, agriculture sector, water quality assessment, pharmaceuticals and tissue engineering. It also looks into the challenges associated and future direction of research in this promising field. This book caters as reference book for researches from the field of nanobiotechnology and biomedical sciences who are interested in the development of rapid, affordable and accurate POCT devices
Notes 6 Conclusion
Online resource; title from PDF title page (SpringerLink, viewed November 3, 2023)
Subject Nanostructured materials.
Smart materials.
Point-of-care testing.
Nanostructured materials.
Point-of-care testing.
Smart materials.
Form Electronic book
Author Mandal, Amit Kumar
Ghorai, Suvankar
Husen, Azamal.
ISBN 9789819957873
9819957877