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Title Plant viral vectors / Kenneth Palmer, Yuri Gleba, editors
Published Berlin ; New York : Springer, [2014]
©2014
Table of Contents
 A Personal History of Virus-Based Vector Construction / William O. Dawson1
 Virus-Derived ssDNA Vectors for the Expression of Foreign Proteins in Plants / Darrin P. Martin19
 Plant Viral Epitope Display Systems for Vaccine Development / Denis Leclerc47
 Applications of Plant Viruses in Bionanotechnology / David J. Evans61
 Milestones in the Development and Applications of Plant Virus Vector as Gene Silencing Platforms / Christophe Lacomme89
 Emerging Antibody-based Products / Larry Zeitlin107
 Production of Recombinant Antigens and Antibodies in Nicotiana benthamiana Using ̀Magnifection' Technology: GMP-Compliant Facilities for Small- and Large-Scale Manufacturing / Hugh Haydon127
 Plant Viral Vectors for Delivery by Agrobacterium / Anatoli Giritch155
 Index193

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Description 1 online resource (x, 194 pages) : color illustrations
Series Current topics in microbiology and immunology, 2196-9965 ; Volume 375
Current topics in microbiology and immunology ; 375.
Contents A Personal History of Virus-Based Vector Construction / William O. Dawson -- Virus-Derived ssDNA Vectors for the Expression of Foreign Proteins in Plants / Edward P. Rybicki and Darrin P. Martin -- Plant Viral Epitope Display Systems for Vaccine Development / Denis Leclerc -- Applications of Plant Viruses in Bionanotechnology / George P. Lomonossoff and David J. Evans -- Milestones in the Development and Applications of Plant Virus Vector as Gene Silencing Platforms / Christophe Lacomme -- Emerging Antibody-based Products / Kevin J. Whaley, Josh Morton, Steve Hume, Ernie Hiatt, Barry Bratcher, Victor Klimyuk [and 3 others] -- Production of Recombinant Antigens and Antibodies in Nicotiana benthamiana Using 'Magnifection' Technology: GMP-Compliant Facilities for Small- and Large-Scale Manufacturing / Victor Klimyuk, Gregory Pogue, Stefan Herz, John Butler and Hugh Haydon -- Plant Viral Vectors for Delivery by Agrobacterium / Yuri Y. Gleba, Daniel Tusé and Anatoli Giritch
Summary In this volume, the authors provide an excellent overview of how far the plant viral vector field has come. This discipline is no longer exclusively the domain of academics − there is a small, but growing number of small biotechnology companies that exploit plant viruses as a platform for commercial innovation in crop improvement, industrial product manufacturing, and human and veterinary health care. The authors, who work in the plant viral ?vectorology? field, have Bill Dawson to thank in some way for their scientific pedigree, and they are honored that he contributed the opening chapter of this volume with the history of plant virus vector development: ?A vector is not a virus; it is a device designed to perform a specific function.? Other contributors have provided fascinating reviews of how plant viral vectors have been adapted to serve specific functions, from plant gene function discovery to nanotechnology, providing infinitely scalable manufacturing systems valuable for human therapeutics.
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (ebrary, viewed May 31, 2016)
Subject Molecular virology.
Plant immunology.
Plant viruses.
Virus diseases of plants.
Genetics -- Technique.
Genetic Techniques
Plant Viruses
TECHNOLOGY & ENGINEERING -- Agriculture -- General.
Genetics -- Technique
Molecular virology
Plant immunology
Plant viruses
Virus diseases of plants
Form Electronic book
Author Gleba, I︠U︡. I︠U︡. (I︠U︡riĭ I︠U︡rʹevich), 1949- editor.
Palmer, Kenneth, editor
ISBN 9783642408298
364240829X
3642408281
9783642408281