Contributors; Preface; 1. Linkage Mapping; 2. Mapping Genomes at the Chromosome Level; 3. Mapping Genomes at the Molecular Level; 4. DNA Sequence of the Human and Other Mammalian Genomes; 5. The Transcriptome; 6. The Proteome; 7. The Epigenome: Epigenetic Regulation of Gene Expression in Mammalian Species; 8. Regulation of Genome Activity and Genetic Networks in Mammals; 9. Inducing Alterations in the Mammalian Genome for Investigating the Functions of Genes; 10. A Comparative Analysis of Mammalian Genomics: Prokaryote and Eukaryote Perspectives; 11. Elements and Mechanisms of Genome Change
Summary
Genomics has experienced a dramatic development during the last 15-20 years. Data from mammalian genomes such as the human, mouse and rat have already been published, while others such as the dog, cattle and chimpanzee will soon follow. This book summarizes the current knowledge of mammalian genomics and offers a comparative analysis of genomes known today. This analysis includes farm, companion and lab animals. Topics covered include structural and functional aspects of the mammalian genome, mechanisms of genomic changes at the molecular level, evolution of DNA sequences, comparative chromoso
