| Description |
1 online resource (xi, 255 pages) |
| Contents |
Overview of sequencing technology platforms / Samuel Myllykangas, Jason Buenrostro, and Hanlee P. Ji -- Applications of high-throughput sequencing / Rodrigo Goya, Irmtraud M. Meyer, and Marco A. Marra -- Computational infrastructure and basic data analysis for high-throughput sequencing / David Sexton -- Base-calling for bioinformaticians / Mona A. Sheikh and Yaniv Erlich -- De novo short-read assembly / Douglas W. Bryant Jr. and Todd C. Mockler -- Short-read mapping / Paolo Ribeca -- DNA-protein interaction analysis (ChIP-Seq) / Geetu Tuteja -- Generation and analysis of genome-wide DNA methylation maps / Martin Kerick, Axel Fischer, and Michal-Ruth Schweiger -- Differential expression for RNA sequencing (RNA-Seq) data : mapping, summarization, statistical analysis, and experimental design / Matthew D. Young [and others] -- MicroRNA expression profiling and discovery / Michael Hackenberg -- Dissecting splicing regulatory network by integrative analysis of CLIP-Seq data / Michael Q. Zhang -- Analysis of metagenomics data / Elizabeth M. Glass and Folker Meyer -- High-throughput sequencing data analysis software : current state and future developments / Konrad Paszkiewicz and David J. Studholme |
| Summary |
The ultimate goal of bioinformatics is to extract biological knowledge out of the large amount of information generated by the scientific community. The chapters compiled in this volume will allow both biologists and computer scientists to understand the significance and potential of this discipline in the analysis of high throughput sequencing data. An essential reference book, not only for serving as guideline for the comprehension of the main data analysis steps, but also for providing new insights into existing software and inspiration to develop new applications |
| Analysis |
Life sciences |
|
Medicine |
|
Human genetics |
|
Bioinformatics |
|
Biomedicine general |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
| Subject |
Bioinformatics.
|
|
Computational Biology -- methods
|
|
Sequence Analysis, RNA -- methods
|
|
Computational Biology
|
|
NATURE -- Reference.
|
|
SCIENCE -- Life Sciences -- Biology.
|
|
SCIENCE -- Life Sciences -- General.
|
|
Bioinformatics
|
| Form |
Electronic book
|
| Author |
Rodríguez-Ezpeleta, Naiara
|
|
Hackenberg, Michael, 1972-
|
|
Aransay, Ana M
|
| ISBN |
9781461407829 |
|
1461407826 |
|
