| Description |
1 online resource (xii, 206 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; 1589 |
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Springer protocols |
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Methods in molecular biology (Clifton, N.J.) ; v. 1589.
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Springer protocols (Series)
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| Contents |
Library construction for high-throughput mobile element identification and genotyping / Hongseok Ha, Nan Wang, and Jinchuan Xing -- Design and optimization of DNA methylation pyrosequencing assays targeting region-specific repeat elements / Gwen Hoad and Kristina Harrison -- Determining epigenetic targets : a beginner's guide to identifying genome functionality through database analysis / Elizabeth A. Hay, Philip Cowie, and Alasdair MacKenzie -- Detecting spatial chromatin organization by chromosome conformation capture II : genome-wide profiling by Hi-C / Matteo Vietri Rudan, Suzana Hadjur, and Tom Sexton -- Quantitative analysis of intra-chromosomal contacts : the 3C-qPCR method / Vuthy Ea, Franck Court, and Thierry Forne -- 5-Hydroxymethylcytosine profiling in human DNA / John P. Thomson, Colm E. Nestor, and Richard R. Meehan -- Adjusting for cell type Composition in DNA methylation data using a regression-based approach / Meaghan J. Jones, Sumaiya A. Islam, Rachel D. Edgar, and Michael S. Kobor -- Correcting for sample heterogeneity in methylome-wide association studies / James Y. Zou -- Nano-MeDIP-seq methylome analysis using low DNA concentrations / Lee M. Butcher and Stephan Beck -- Bisulfite conversion of DNA from tissues, cell lines, buffy coat, FFPE tissues, microdissected cells, swabs, sputum, aspirates, lavages, effusions, plasma, serum, and urine / Maria Jung, Barbara Uhl, Glen Kristiansen, and Dimo Dietrich -- Analysis of imprinted gene regulation / David A. Skaar and Randy L. Jirtle -- Statistical methods for methylation data / Graham W. Horgan and Sok-Peng Chua |
| Summary |
This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable to further study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Population Epigenetics: Methods and Protocols aims to aid population researchers in exploiting the latest insights into epigenetics to improve our understanding of the factors that influence human health and longevity |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerProtocol, viewed February 20, 2017) |
| Subject |
Epigenetics -- Laboratory manuals
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Genetics -- Laboratory manuals
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Population genetics.
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Epigenesis, Genetic -- genetics
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Genetics, Population
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Medical genetics.
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Medical -- Genetics.
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Population genetics
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Epigenetics
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Genetics
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| Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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| Form |
Electronic book
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| Author |
Harrison, Kristina, editor
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Haggarty, Paul, editor
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| ISBN |
9781493969036 |
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149396903X |
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