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E-book

Title Antibiotics and antimicrobial resistance eenes : environmental occurrence and treatment technologies / Muhammad Zaffar Hasmi, editor
Published Cham : Springer, 2020

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Description 1 online resource (466 pages)
Series Emerging Contaminants and Associated Treatment Technologies
Emerging contaminants and associated treatment technologies.
Contents Intro -- Preface -- Acknowledgments -- About the Book -- Abbreviations -- Contents -- Contributors -- Chapter 1: Entry Routes of Antibiotics and Antimicrobial Resistance in the Environment -- 1.1 Introduction -- 1.2 Characterization of Entry Routes -- 1.2.1 Manure -- 1.2.2 Wastewater Treatment Plants (WWTPs) -- 1.2.3 Aquaculture -- 1.2.4 Airborne ARGs -- 1.3 Mutual Interactions: A Conceptual Model for Understanding Entry Routes of Antibiotics, ARB, and ARGs -- 1.4 Summary and Perspectives -- References -- Chapter 2: Antibiotics Use in Hospitals and Their Presence in the Associated Waste
2.6 Conclusion -- References -- Chapter 3: Antimicrobial and Antibiotic Resistance Genes in the Environment -- 3.1 Introduction -- 3.2 Antimicrobial Resistance -- 3.3 Origin of Resistance Genes -- 3.4 Horizontal Spread of Antimicrobial Resistance Genes -- 3.5 Assembly of Factors for Formation of Resistance -- 3.6 Compatibility for Development of Resistance -- 3.7 Hazardous Effects of Environments to Human Health -- 3.8 Resistance Genes in Different Environments/Habitats -- 3.8.1 Ocean -- 3.8.2 Air -- 3.8.3 Soil -- 3.9 Pathways of Resistance
3.10 Antimicrobials Co-selectors and Resistant Pathogens in Environment -- 3.11 Mitigating Discharge of Antimicrobials in Environment -- 3.12 Antibiotic and Antibiotic Extended Resistomes -- 3.13 Novel Genes Formation Related to Antimicrobial Pathogens -- 3.14 Aminoglycosides Affected by Methylase Activity of rRNA -- 3.15 Methyltransferase Activity Against Linezolid -- 3.16 Plasmid-Mediated Quinolone Resistance Associated with Efflux Pumps -- 3.17 Proteins Protecting Qnr Topoisomerases -- 3.18 CTX-M ESBLs -- 3.19 Future of Resistant "Superbugs" -- 3.20 Conclusion -- References
Chapter 4: Global and Temporal Trends in the Use of Antibiotics and Spread of Antimicrobial Resistance -- 4.1 Introduction -- 4.2 Genetic Basis of Antibiotic Resistance -- 4.3 Biochemical Routes Associated with Antibiotic Resistance -- 4.3.1 Alteration of Antibiotic Agents -- 4.3.1.1 Chemical Modification of Antibiotic Molecules -- 4.3.2 Inhibiting the Penetration/Attachment of Antibiotic Molecule to Specific Target -- 4.3.3 Modification of Target Sites -- 4.3.3.1 Protection of Target Sites -- 4.4 Global and Temporal Trends in the Use of Antibiotics
Summary This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including their entry routes in soil, air, water and sediment, their use in hospital and associated waste, global and temporal trends in use and spread of antibiotics, AMR and ARG. Antimicrobial/antibiotic resistance genes due to manure and agricultural waste applications, bioavailability, biomonitoring, and their Epidemiological, ecological and public health effects. The book addresses the antibiotic and AMR/ARG risk assessment and treatment technologies, for managing antibiotics and AMR/ARG impacted environments The book's expert contributions span 26 chapters, and offer a comprehensive framework for better understanding and analyzing the environmental and social impacts of antibiotics and AMR/ARGs. Readers will have access to recent and updated models regarding the interpretation of antibiotics and AMR/ARGs in environment and biomonitoring studies, and will learn about the management options require to appropriately mitigate environmental contaminants and pollution. The book will be of interest to students, teachers, researchers, policy makers and environmental organizations
Notes 4.5 Global and Temporal Trends of Antimicrobial Resistance
Includes index
Print version record
Subject Antibiotics.
Drug resistance in microorganisms.
Epidemiology & medical statistics.
Microbiology (non-medical)
Environmental science, engineering & technology.
Medical microbiology & virology.
Environmental medicine.
Pollution & threats to the environment.
Medical -- Epidemiology.
Science -- Life Sciences -- Biology -- Microbiology.
Technology & Engineering -- Environmental -- General.
Medical -- Microbiology.
Medical -- Public Health.
Science -- Environmental Science.
Antibiotics
Drug resistance in microorganisms
Form Electronic book
Author Hashmi, Muhammad Zaffar.
ISBN 3030404226
9783030404222