| Description |
1 online resource (100 pages) |
| Contents |
Editor and author biographies; Abbreviations; 1 Introduction; Reference; 2 Epidemiology, pathogenesis, and etiology of acute leukemia; Epidemiology and incidence; International and US statistics; Age, sex, and ethnicity-related differences; Biology and pathogenesis of acute leukemia; Etiology of acute leukemia; Exposure to ionizing radiation; Exposure to benzene; Way of living; Genetic conditions; Preceding blood and marrow disorders: secondary acute myeloid leukemia; Prior chemotherapy; Autoimmune conditions; Viruses; References; 3 Clinical manifestations and diagnosis |
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Clinical presentation of acute leukemiaDiagnostic testing and criteria; Morphology; Immunophenotyping; Cytogenetics and molecular testing; Lumbar puncture; Differential diagnosis; Additional work-up for patients with acute leukemias; Recommended pretreatment work-up; Special considerations in older patients; References; 4 Diagnostic criteria, classification, and prognosis of acute leukemias; Diagnostic criteria and classification of acute myeloid leukemia; Acute myeloid leukemia with recurrent genetic changes; Acute myeloid leukemia with myelodysplasia-related changes |
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Therapy-related myeloid neoplasmsAcute myeloid leukemia, not otherwise specified; Rare entities; Outlook: the 2016 revision of the World Health Organization classification; Diagnostic criteria and classification of lymphoblastic leukemias; B-cell lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities; Recent developments in acute lymphoblastic leukemia; Diagnostic criteria and classification of acute leukemias of ambiguous lineage; Prognostic factors in acute myeloid leukemia; Medical Research Council classification; European LeukemiaNet classification; Gene mutations |
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Other risk factors and prognostic scoring systemsMinimal residual disease; Prognostic factors in acute lymphoblastic leukemia; References; 5 Therapeutic management of acute myeloid leukemia; Overview of treatment options; Treatment by phase; Remission induction; Supportive therapy; Post-remission therapy; Resistant and relapsed leukemia; Treatment of the medically unfit and elderly patient; References; 6 Therapeutic management of acute promyelocytic leukemia; Overview of treatment options; Treatment by risk group and phase; European LeukemiaNet recommendations; Management after consolidation |
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Treatment of low/intermediate risk patients according to the APL0406 studyTreatment of high risk patients (WBC>10G/L at diagnosis) according to AIDA; Relapse treatment options; Supportive management of acute promyelocytic leukemia according to the European LeukemiaNet recommendations; References; 7 Therapeutic management of acute lymphoblastic leukemia; General approach for management of acute lymphoblastic leukemia; Prognostic factors and risk-adapted therapy; Clinical trials supporting current treatment algorithms in first-line therapy; Induction regimens for Ph-negative ALL |
| Summary |
This book provides an overview of the key developments in both acute lymphocytic leukemia and acute myeloid leukemia with a comprehensive guide to the epidemiology, pathogenesis, etiology, clinical manifestations, classification, diagnosis, and staging as well as the most recent developments in the therapeutic landscape for acute leukemia. The Handbook of Acute Leukemia offers readers a key resource into the future outlook for patients with leukemia and is edited and authored by internationally renowned experts in the field. Leukemia is cancer of the white blood cells and acute leukemia means the condition progresses rapidly and aggressively, requiring immediate treatment. Acute leukemia is classified according to the type of white blood cells that are affected: either lymphocytes and myeloid cells |
| Notes |
Induction regimens for |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Acute leukemia -- Handbooks, manuals, etc
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Acute myeloid leukemia.
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Lymphocytic leukemia.
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Leukemia, Myeloid, Acute
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Leukemia, Lymphoid
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HEALTH & FITNESS -- Holism.
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HEALTH & FITNESS -- Reference.
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MEDICAL -- Alternative Medicine.
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MEDICAL -- Atlases.
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MEDICAL -- Essays.
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MEDICAL -- Family & General Practice.
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MEDICAL -- Holistic Medicine.
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MEDICAL -- Osteopathy.
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Lymphocytic leukemia
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Acute myeloid leukemia
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Acute leukemia
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| Genre/Form |
handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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| Form |
Electronic book
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| Author |
Hiddemann, W.
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| ISBN |
9783319267722 |
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3319267728 |
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