| Description |
1 online resource (381 pages) |
| Contents |
Key Concepts in Assay Development, Screening and the Properties of Lead and Candidate Compounds -- Application of Fragment-based Approaches to the Discovery of Drugs for Neglected Tropical Diseases -- Chemical Hybridization Approaches Applied to Natural and Synthetic Compounds for the Discovery of Drugs Active Against Neglected Tropical Diseases -- Current Inhibitors of Dengue Virus: An Overview -- Overview of Drugs used Against Zika Virus -- Chikungunya Virus Infection: A Review of its Control and Treatment -- Recent Advances in Repositioning Non-Antibiotics against Tuberculosis and other Neglected Tropical Diseases -- Prospects of Pre-clinical [6.6.0] Bicyclic Nitrogen Heterocycles in the Treatment of Tuberculosis -- Progress in Antimalarial Drug Discovery and Development -- Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections -- New Chemical Scaffolds to Selectively Target the Trypanothione Metabolism -- Renewal of Interest in Nitroaromatic Drugs: Towards New Anti-Kinetoplastid Agents -- New Biological Targets for the Treatment of Leishmaniasis -- Curcumin and Neglected Infectious Diseases -- Overview of Helminthiasis: Current State and Future Directions |
| Summary |
This book consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Tropical medicine.
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Drug development.
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Anti-infective agents.
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Tropical Medicine
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Anti-Infective Agents
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MEDICAL -- Infectious Diseases.
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MEDICAL -- Pharmacy.
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SCIENCE -- Chemistry -- General.
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Tropical medicine
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Anti-infective agents
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Drug development
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| Form |
Electronic book
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| Author |
Jayaprakash, Venkatesan, editor.
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Castagnolo, Daniele, editor
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Özkay, Yusuf, editor
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| ISBN |
9781351011648 |
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1351011642 |
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9781351011655 |
|
1351011650 |
|
9781351011624 |
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1351011626 |
|
1351011634 |
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9781351011631 |
|
