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E-book

Title Evolution of extracellular matrix / Fred W. Keeley, Robert P. Mecham, editors
Published Berlin ; New York : Springer, ©2013

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Description 1 online resource
Series Biology of extracellular matrix, 0887-3224
Biology of extracellular matrix (Springer (Firm))
Contents Extracellular Matrix Evolution: An Overview / Josephine C. Adams -- Domain Shuffling and the Evolution of Vertebrate Extracellular Matrix / Hiroshi Wada -- Invertebrate and Vertebrate Collagens / Jean-Yves Exposito, Claire Lethias -- The Evolution of Elastin / Fred W. Keeley -- Evolutionary Insights into Fibrillin Structure and Function in the Extracellular Matrix / Sacha Jensen, David Yadin, Ian Robertson -- Molecular Evolution of the Microfibril-Associated Proteins: The Fibulins and the MAGPs / Fernando Segade -- Evolution and Function of SPARC and Tenascins: Matricellular Counter-Adhesive Glycoproteins with Pleiotropic Effects on Angiogenesis and Tissue Fibrosis / Cristina A. Baratta, Theodore J. Brown -- Thrombospondins and Their Receptors: Evolving Functions / David D. Roberts, William A. Frazier -- Evolution of Cell Adhesion to Extracellular Matrix / Mark S. Johnson, Jarmo Käpylä, Konstantin Denessiouk
Summary The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology
Analysis Life sciences
Cytology
Evolution (Biology)
Cell Biology
Cell Physiology
Notes Includes index
Bibliography Includes bibliographical references and index
Subject Extracellular matrix.
Evolution (Biology)
Biological Evolution
Extracellular Matrix
evolution.
MEDICAL -- Anatomy.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Evolution (Biology)
Extracellular matrix
Form Electronic book
Author Keeley, Fred W
Mecham, Robert P.
ISBN 9783642360022
3642360025
3642360017
9783642360015