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Title Pediatric brain stimulation : mapping and modulating the developing brain / edited by Adam Kirton, Donald L. Gilbert
Published London, UK : Academic Press is an imprint of Elsevier, 2016

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Description 1 online resource
Contents Front Cover; PEDIATRIC BRAIN STIMULATION; How to Use; PEDIATRIC BRAIN STIMULATION; Copyright; Contents; List of Contributors; Foreword; Preface; I -- FUNDAMENTALS OF NIBS IN CHILDREN; 1 -- TMS Basics: Single and Paired Pulse Neurophysiology; INTRODUCTION; HOW DOES TMS WORK?; Principle of TMS; Types of TMS Coil; NEURONAL STRUCTURES ACTIVATED BY TMS; Stimulation of the Motor Cortex; Descending Volleys; Descending Pathways from the Cerebral Cortex; Motor-Evoked Potential; Motor Thresholds; TMS NEUROPHYSIOLOGY; Single-Pulse TMS; Stimulus Response Curve; Silent Periods; Paired-pulse TMS
Short-Interval Intercortical Inhibition (SICI)Intracortical Facilitation (ICF); Short-Interval Intracortical Facilitation (SICF); Long-Interval Intracortical Inhibition (LICI); Interhemispheric Inhibition (IHI); TMS Paired With Sensory Activation; Short-Latency Afferent Inhibition (SAI); Paired Associative Stimulation (PAS); Repetitive TMS; TMS RELIABILITY; TMS SAFETY; References; 2 -- Assessing Normal Developmental Neurobiology With Brain Stimulation; INTRODUCTION; NORMAL DEVELOPMENTAL NEUROBIOLOGY; Theoretical Background of Excessive Production of Synapses/Pruning of Synaptic Connectivity
Structural Changes to the Developing BrainDifferent Aspects of Neuromotor Development; TMS-EVOKED PARAMETERS THAT REFLECT NEUROMOTOR MATURATION; Age Specificity of Resting Motor Threshold; Maturational Aspects of MEP Latencies and CMCT; Ipsilateral Versus Contralateral Projections -- MEP Amplitudes (Contra-vs. Ipsilateral); Intracortical Inhibition and Connectivity Between Brain Areas -- Silent Period, Intracortical Inhibition Paradigms, Interhemisphe ... ; Synaptic Plasticity; ASSESSING NEUROPHYSIOLOGIC FUNCTIONING WITH BRAIN STIMULATION IN DEVELOPMENT AND DEVELOPMENTAL DISORDERS; Cerebral Palsy
Attention Deficit Hyperactivity Disorder (ADHD)Autism Spectrum Disorders (ASDs); RASopathies; OUTLOOK; Cortical Maps/Presurgical Mapping/Virtual Lesion Technique; TMS and Other Neuroimaging Methods; Neuromodulation/Therapeutic Applications of TMS; References; 3 -- Neuroplasticity Protocols: Inducing and Measuring Change; BACKGROUND (IN VITRO AND ANIMAL WORK); Hebbian/Konorski Theories of Plasticity; Mammalian Brain and Hippocampus; Theta Burst Stimulation (TBS): A Physiological Approach to LTP Induction; Physiological Significance of LTP
OVERVIEW OF REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS)TYPES OF RTMS; Conventional rTMS; Very Low-Frequency rTMS; <"neHz rTMS;>OneHz rTMS ("High"-Frequency rTMS); Paired Associative Stimulation (PAS); Theta Burst Stimulation (TBS); Repetitive Paired-Pulse (PPS) and Quadripulse Stimulation (QPS); Metaplasticity; STUDY DESIGN CONSIDERATIONS; Type of Studies; Patient Selection and Safety; rTMS Procedure; Statistical Analysis; CONCLUSION; References; 4 -- Therapeutic rTMS in Children; INTRODUCTION: FROM BIOMARKER OF PLASTICITY AND EXCITABILITY TO INDUCER OF THERAPEUTIC CHANGES?
Summary Pediatric Brain Stimulation: Mapping and Modulating the Developing Brain presents the latest on this rapidly expanding field that has seen an exponential growth in publications over the past 10 years. Non-invasive modalities like TMS can painlessly map and measure complex neurophysiology in real patients. Neuromodulatory applications like rTMS and tDCS carry increasingly proven therapeutic applications. Rapidly advancing technological methodologies are increasing opportunities and indications. Despite all these benefits, applications in the more plastic developing brains of children are only just emerging. This book provides a comprehensive overview of brain stimulation in children. Chapters include Transcranial Magnetic Stimulation (TMS) fundamentals, brain stimulation in pediatric neurological conditions, and invasive brain stimulation. The main audience for this research will be those interested in applying brain stimulation technologies to advance clinical research and patient care, although a wide variety of clinicians and scientist will find this to be a valuable reference on brain stimulation with specific chapters on a variety of conditions. Provides an overview of recent findings and knowledge of pediatric brain stimulation and the developing brainEdited by renowned leaders in the field of pediatric brain stimulationPresents a great resource for basic and clinical scientists and practitioners in neuroscience, neurology, neurosurgery, and psychiatry
Notes Includes index
Online resource; title from PDF title page (ScienceDirect, viewed May 19, 2016)
Subject Brain stimulation.
Pediatric neurology.
MEDICAL -- Gynecology & Obstetrics.
Brain stimulation
Pediatric neurology
Form Electronic book
Author Kirton, Adam, editor
Gilbert, Donald L. (Pediatric neurologist), editor.
ISBN 9780128020388
0128020385
0128020016
9780128020012