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Title Lipoproteins in diabetes mellitus / Alicia J. Jenkins, Peter P. Toth, Timothy J. Lyons, editors
Published New York : Humana Press, 2014
Table of Contents
1.Laboratory Assessment of Lipoproteins in Diabetes / Barry Lewis1
2.Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin-Resistant Diabetes / Eliot A. Brinton11
3.Insulin Resistance and Atherosclerosis / Vasudevan A. Raghavan41
4.Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes / Thomas D. Dayspring55
5.Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes / Daphne Owens101
6.Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States / Alberico L. Catapano125
7.Lipoprotein(a): Structure, Metabolism, and Pathophysiology / Gerhard M. Kostner141
8.Lipoprotein Glycation in Diabetes Mellitus / Andrzej S. Januszewski157
9.Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus / Tony Hayek187
10.The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes / Gabriel Virella203
11.Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes / Peter J. Little215
12.Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus / Richard L. Klein231
13.Endothelial Dysfunction and Dyslipidemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy / Gerald F. Watts239
14.Lipoproteins and Diabetic Nephropathy / Per-Henrik Groop279
15.Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy / Timothy J. Lyons301
16.Effects of Lifestyle (Diet, Plant Sterols, Exercise) and Glycemic Control on Lipoproteins in Diabetes / Peter Clifton315
17.About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus / Val Gebski329
18.Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Steven R. Jones347
19.The PPAR System in Diabetes / Christelle Foucher357
20.Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Eliot A. Brinton373
21.Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / James A. Underberg399
22.Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus / Harold Bays415
23.Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes / Alicia J. Jenkins435
 Index455

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Description 1 online resource (x, 1022 pages) : illustrations
Series Contemporary diabetes
Contemporary diabetes.
Contents 1. Laboratory Assessment of Lipoproteins in Diabetes / Barry Lewis -- 2. Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin-Resistant Diabetes / Eliot A. Brinton -- 3. Insulin Resistance and Atherosclerosis / Vasudevan A. Raghavan -- 4. Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes / Thomas D. Dayspring -- 5. Lipoprotein Metabolism and Alterations Induced by Insulin Resistance and Diabetes / Daphne Owens -- 6. Production and Metabolism of Triglyceride-Rich Lipoproteins in Both the Normal and Diabetic States / Alberico L. Catapano -- 7. Lipoprotein(a): Structure, Metabolism, and Pathophysiology / Gerhard M. Kostner -- 8. Lipoprotein Glycation in Diabetes Mellitus / Andrzej S. Januszewski -- 9. Lipoprotein (LDL and HDL) Oxidation in Diabetes Mellitus / Tony Hayek
10. The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes / Gabriel Virella -- 11. Lipid: Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes / Peter J. Little -- 12. Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus / Richard L. Klein -- 13. Endothelial Dysfunction and Dyslipidemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy / Gerald F. Watts -- 14. Lipoproteins and Diabetic Nephropathy / Per-Henrik Groop -- 15. Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy / Timothy J. Lyons -- 16. Effects of Lifestyle (Diet, Plant Sterols, Exercise) and Glycemic Control on Lipoproteins in Diabetes / Peter Clifton -- 17. About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus / Val Gebski
18. Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Steven R. Jones -- 19. The PPAR System in Diabetes / Christelle Foucher -- 20. Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / Eliot A. Brinton -- 21. Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients / James A. Underberg -- 22. Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus / Harold Bays -- 23. Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes / Alicia J. Jenkins
Summary Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes
Notes Includes index
Print version record
In Springer eBooks
Subject Diabetes.
Diabetes -- Molecular aspects
Lipoproteins.
Diabetes Mellitus
Lipoproteins
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Médecine.
Diabetes
Diabetes -- Molecular aspects
Lipoproteins
Form Electronic book
Author Jenkins, Alicia J., editor.
Toth, Peter P., editor
Lyons, Timothy J., editor.
ISBN 9781461475545
1461475546