| Description |
1 online resource (296 pages) |
| Contents |
Intro; Acknowledgments; Contents; About the Editors; Part I: Clinical Aspects of Fatty Liver Disease; 1: Clinical Aspects of Alcoholic Liver Disease; 1.1 The Burden of Alcoholic Liver Disease; 1.2 Natural History of Alcoholic Liver Disease; 1.2.1 Simple Steatosis; 1.2.2 Steatohepatitis; 1.2.3 Liver Fibrosis; 1.2.4 Cirrhosis; 1.2.5 Timely Identification and Intervention for Alcoholic Liver Disease; 1.3 Clinical Unmet Needs; 1.3.1 Natural History; 1.3.2 Pathophysiology; 1.3.3 Non-invasive Markers; 1.3.4 Treatment Options; 1.3.5 Implementation; 1.4 The Gut-Liver Cross Talk |
|
1.5 A Hypothesis of the Pathogenesis of Alcoholic Liver Disease1.5.1 Gut Microbiome in Alcoholic Liver Disease; 1.5.2 Gut Barrier Function in Alcohol Liver Disease; 1.5.3 The Toxic Effect of Alcohol; 1.5.4 The Immune System in Alcoholic Liver Disease; 1.5.5 Bile Acids and Alcoholic Liver Disease; 1.6 From Hypothesis to Understanding; 1.7 Interventions Targeting the Gut to Treat Alcoholic Fatty Liver Disease; 1.7.1 Antibiotics; 1.7.2 Probiotics, Prebiotics and Synbiotics; 1.7.3 Faecal Microbiome Transplantation; 1.7.4 Adsorbants; 1.7.5 Bile Acid Modulators; 1.8 Conclusion |
|
2.5.2 Non-invasive Detection of Liver Steatosis and Inflammation2.5.3 Non-invasive Detection of Liver Fibrosis; 2.5.4 Liver Biopsy: Who and Why; 2.6 Histological Characteristics and Scoring Systems; 2.6.1 Fibrosis; 2.7 Natural History of NAFLD; 2.7.1 Liver Related Disease Risk; 2.7.2 Cardiovascular Disease Risk; 2.8 Treatment of NAFLD; 2.8.1 Lifestyle Intervention; 2.8.2 Pharmacological Treatment; 2.9 Conclusion; References; 3: Impact of Childhood Obesity in Fatty Liver Disease; 3.1 BMI; 3.2 Tracking; 3.3 Body Composition; 3.4 Causes of Childhood Obesity |
|
3.5 Ectopic Fat in the Liver3.6 Assessment of Ectopic Fat in the Liver; 3.7 Treatment of Ectopic Fat in the Liver; 3.8 Treatment of Children with Obesity; References; 4: Fetal Programming of Fatty Liver Disease; 4.1 Introduction; 4.2 Fetal Programming of Adult Disease; 4.3 Mechanisms of Fetal Programming; 4.4 Fatty Liver Disease; 4.5 Fetal Programming of Fatty Liver Disease; 4.5.1 Fetal Undernutrition and Hepatic Fat Accumulation; 4.5.2 Fetal Overnutrition and Hepatic Fat Accumulation; 4.6 Programming of NAFLD by Epigenetic Mechanisms; 4.6.1 DNA Methylation |
| Summary |
The book brings together the current knowledge and future perspectives of the complex physiology and pathophysiology of gut-liver interactions in health and disease. It provides readers with a unique overview and access to knowledge that cannot be obtained elsewhere. The structure is logical and covers all aspect including the normal physiology, changes in various liver diseases, technology, sample collection and various interventions. Thus suitable for general reading, lookup for specific questions or as a reference book within the area. The book allows the reader to access all the knowledge that has been generated within the last 10 years in this field |
| Bibliography |
References2: Adult Non-alcoholic Fatty Liver Disease (NAFLD) ; 2.1 Introduction; 2.2 Definition and Aspects of NAFLD; 2.3 Risk Factors for Development of NAFLD and Concomitant Metabolic Disorders in NAFLD; 2.3.1 Obesity and Visceral Adiposity; 2.3.2 Insulin Resistance and Metabolic Syndrome; 2.3.3 Genetics, Age and Ethnicity; 2.4 NAFLD Pathophysiology; 2.4.1 Hepatic Steatosis and Lipotoxicity; 2.4.2 Adipose Tissue Inflammation and Dysfunction; 2.4.3 Gut Microbiota and Gut-Liver Axis; 2.5 Diagnosis of NAFLD; 2.5.1 Who to Screen for NAFLD and Why Diagnose NAFLD |
| Notes |
4.6.2 Histone Modifications |
|
Includes index |
|
Print version record |
| Subject |
Liver -- Diseases.
|
|
Gastroenterology.
|
|
Gastrointestinal system -- Microbiology.
|
|
Liver Diseases
|
|
Gastrointestinal Tract
|
|
Risk Factors
|
|
Gastroenterology
|
|
HEALTH & FITNESS -- Diseases -- General.
|
|
MEDICAL -- Clinical Medicine.
|
|
MEDICAL -- Diseases.
|
|
MEDICAL -- Evidence-Based Medicine.
|
|
MEDICAL -- Internal Medicine.
|
|
Gastroenterology
|
|
Gastrointestinal system -- Microbiology
|
|
Liver -- Diseases
|
| Form |
Electronic book
|
| Author |
Krag, Aleksander
|
|
Hansen, Torben
|
| LC no. |
2018959617 |
| ISBN |
9783319988900 |
|
3319988905 |
|
