| Description |
1 online resource (xi, 185 pages) : illustrations |
| Series |
2012-2013 Springer E-Books - Biomedical & Life Sciences
|
| Contents |
The Biology of Toll-Like Receptors and NOD-Like Receptors: The Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in TLR4 Gene and Cancer -- Structural Genomic Variation in Other Toll-Like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots in the Field: Where Should We Go? |
| Summary |
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed |
| Analysis |
patroonherkenning |
|
pattern recognition |
|
immunologie |
|
immunology |
|
receptoren |
|
receptors |
|
neoplasms |
|
oncologie |
|
oncology |
|
humane genetica |
|
human genetics |
|
cardiologie |
|
cardiology |
|
genomica |
|
genomics |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Online resource; title from PDF title page (SpringerLink, viewed September 3, 2013) |
| Subject |
Cell receptors.
|
|
Genetics.
|
|
Genomics.
|
|
Cardiovascular Diseases -- therapy
|
|
Genomics
|
|
Neoplasms -- therapy
|
|
Receptors, Pattern Recognition
|
|
Receptors, Cell Surface
|
|
Genetics
|
|
genetics.
|
|
SCIENCE -- Life Sciences -- Biochemistry.
|
|
Genomics
|
|
Cell receptors
|
|
Genetics
|
| Form |
Electronic book
|
| Author |
Yuzhalin, Arseniy E., author.
|
| ISBN |
9783034806886 |
|
3034806884 |
|
3034806876 |
|
9783034806879 |
|
