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E-book

Title Sex differences in cardiovascular physiology and pathophysiology / edited by Babbette LaMarca, Barbara T. Alexander
Edition First edition
Published London : Academic Press, an imprint of Elsevier, [2019]
©2019

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Description 1 online resource
Contents Front Cover; Sex Differences in Cardiovascular Physiology and Pathophysiology; Copyright; Contents; Contributors; Introduction to Sex Differences in Cardiovascular Physiology; References; Part I: Sex Steroid Receptors; Chapter 1: Androgens and Cardiovascular Diseases in Women; Introduction; Androgens and Cardiovascular Disease in Women; Androgens and Blood Pressure Regulation in Women; The Hyperandrogenemic Female Rat, a Model of Polycystic Ovary Syndrome; The Aging Female Spontaneously Hypertensive Female Rat (PMR); Mechanisms by Which Androgens Can Increase BP in Women
Renin-Angiotensin-Aldosterone SystemEndothelin System; Sympathetic Nervous System; 20-HETE; Oxidative stress; Androgens and Obesity in Women; Androgens and Androgen Receptor Action in Women; Summary; References; Chapter 2: Estrogen Receptor Signaling and Cardiovascular Function; Introduction; Estrogen Receptors; Vascular Effects of Estrogen; Atherosclerosis; Cardiac Effects of Estrogens; Estrogen and the Renin-Angiotensin-Aldosterone System (RAAS); Hormone Replacement and Cardiovascular Health; References
Chapter 3: The Protective Role of Estrogen and Brain Estrogen Receptors in the Pathogenesis of HypertensionIntroduction; The Neural Control of BP and Estrogen Receptors in the CNS; Estrogen Actions and Neurally Mediated Protection Against Hypertension; The Sympathetic Nervous System; Estrogen, Sex, and the Baroreceptor Reflex; ER in CNS Sites and the Protective Actions of Estrogen; SFO; AP; NTS; PVN; RVLM; Cellular and Molecular Mechanisms of Estrogen Action in the Brain and Protection Against Hypertension; Oxidase Stress and Nitric Oxide System in the CNS
Interactions Between Estrogen and RAAS Antihypertensive Axis in the CNSRole of Estrogen in Protection against Sensitization of ANG II Hypertension; Summary and Conclusion; Acknowledgments; References; Chapter 4: Sex Differences in Cerebral Ischemia; Sex Differences in Clinical Stroke; Sex and Ischemic Stroke Incidence and Prevalence; Sex and Ischemic Stroke Mortality; Sex and Ischemic Stroke Morbidity; Potential Mediators of Sex Differences in Stroke Outcome; Age; Cardiovascular Risk Factors; Stroke Subtype; Stroke Symptoms; Stroke Care; Sex Differences in Stroke Risk Factors
Unique Stroke Risk FactorsOral Contraceptive Pills (OCP); Pregnancy; Early Menopause; Hormone Replacement Therapy (HRT); Androgens; Shared Stroke Risk Factors; Atrial Fibrillation; Migraine; Depression; Cellular Mechanisms of Sex Differences in Ischemic Stroke; Considering Sex Differences in Clinical Stroke Trials; Sex in Experimental Modes of Ischemic Stroke; In Vitro; In Vivo; Pathophysiology of Cerebral Ischemia; Sex Differences in Mitochondrial Metabolism; Sex Differences in Cell Death After Stroke; Sex Differences in Endothelial Cell and Astrocyte Function After Cerebral Ischemia
Summary Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed April 15, 2019)
Subject Cardiovascular system -- Physiology
Cardiovascular system -- Pathophysiology
Sex differences.
Sex factors in disease.
Cardiovascular Physiological Phenomena
Sex Factors
Cardiovascular System -- physiopathology
Sex Characteristics
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
Sex factors in disease
Cardiovascular system -- Pathophysiology
Cardiovascular system -- Physiology
Sex differences
Genre/Form Electronic books
Form Electronic book
Author LaMarca, Babbette, editor
Alexander, Barbara T., editor.
ISBN 9780128131985
0128131985