| Description |
1 online resource (viii, 153 pages) : illustrations (some color) |
| Contents |
Contributors; 1: Craniopharyngiomas: Natural History and Clinical Presentation; 1.1 Introduction; 1.2 History; 1.3 Epidemiology; 1.4 Presentation (Clinical and Hormonal Manifestations); References; 2: Craniopharyngioma: Pathological and Molecular Aspects; 2.1 An Historical Note; 2.2 Adamantinous Craniopharyngioma; 2.2.1 Macroscopic Features; 2.2.2 Microscopic Features; 2.2.3 Electron Microscopy; 2.3 Papillary Craniopharyngioma; 2.3.1 Macroscopic Features; 2.3.2 Microscopic Features; 2.3.3 Electron Microscopy; 2.4 The Immunoprofile of Craniopharyngioma |
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2.5 Can Pathology Predict Recurrence?2.5.1 Invasion in Craniopharyngioma and Its Implications; 2.6 Ectopic Locations; 2.7 Metastatic Craniopharyngioma; 2.8 Malignancy in Craniopharyngioma; 2.9 Differential Diagnosis: Lesions Mimicking Craniopharyngioma; 2.10 Craniopharyngioma Can Occur in Association with Other Sellar Lesions; 2.11 Molecular Aspects and Pathogenesis; 2.11.1 Molecular Aetiology of Adamantinous Craniopharyngioma; 2.11.2 Stem Cells Play a Critical Role in ACP Tumorigenesis; 2.11.3 The EGFR and SHH Pathways Are Upregulated in Mouse and Human ACP |
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2.11.4 Molecular Aetiology of Papillary CraniopharyngiomaReferences; 3: Neuroradiological Diagnosis of Craniopharyngiomas; 3.1 Introduction; 3.2 Imaging Technique; 3.3 General Features; 3.4 Adamantinous Subtype; 3.5 Papillary Subtype; 3.6 Differential Diagnosis; References; 4: Transsphenoidal Approaches to Craniopharyngiomas; 4.1 Introduction; 4.2 Transsphenoidal Approaches; 4.2.1 Microscopic Transsphenoidal Approaches; 4.2.1.1 Sublabial; 4.2.1.2 Endonasal; 4.2.2 Transsphenoidal Transsellar Transdiaphragmatic Approach; 4.2.3 Transsphenoidal Transtuberculum Sellae Approach |
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4.2.3.1 Cystic Suprasellar Craniopharyngiomas4.2.3.2 Endoscopic Endonasal; 4.2.4 Anterior Skull Base Endoscopic Approach; 4.2.5 Combined Approaches; 4.3 Endonasal Transsphenoidal Operative Technique; 4.3.1 Preoperative Phase; 4.3.2 Operating Room Layout and Patient Positioning; 4.3.3 Surgical Procedure; 4.3.3.1 Nasal Phase (Single Surgeon/Two Hands); 4.3.3.2 Sphenoidal Phase (Two Surgeons, Three or Four Hands); 4.3.3.3 Sellar Phase; 4.3.4 Closure; 4.4 Adjuvant Therapy; 4.4.1 Intracavitary Radioisotopes; 4.4.2 Intracavitary Chemotherapy; 4.4.3 Interferon Therapy; 4.5 Outcomes |
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ConclusionReferences; 5: Surgical Approach to Craniopharyngiomas: Transcranial Routes; 5.1 Introduction; 5.2 Anatomic Consideration for Surgical Planning; 5.3 Surgical Indications; 5.4 Surgical Anatomy; 5.5 Technique; 5.5.1 FOZ; 5.5.2 CISTA; 5.6 Clinical Series; 5.6.1 Patient Population; 5.6.2 Early Postoperative Results; 5.6.3 Tumor Recurrence; 5.6.4 Further Treatments and Disease Status at Last Follow-Up; References; 6: Radiotherapy and Radiosurgery for Craniopharyngiomas; 6.1 Introduction; 6.2 Radiotherapy and Radiosurgery; 6.2.1 Fractionated Stereotactic Radiotherapy |
| Summary |
This book provides up-to-date coverage of the most relevant topics in the diagnosis and management of craniopharyngiomas. After introductory discussion of natural history and clinical presentation, individual chapters are devoted to pathological and molecular aspects, use of diagnostic imaging techniques, the surgical approach to craniopharyngiomas, radiotherapy and radiosurgery, and associated endocrine disturbances. A particular feature of the book is the detailed attention devoted to the metabolic consequences of the disease and related treatments, including obesity and electrolyte disturbances, and to cognitive alterations. This book will be of value to oncologists, neurosurgeons, and endocrinologists by assisting in diagnostic workup, delivery of appropriate treatment, and management of the serious metabolic and endocrine consequences |
| Bibliography |
Includes bibliographical references |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed April 13, 2016) |
| Subject |
Brain -- Tumors -- Diagnosis.
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Brain -- Tumors -- Treatment
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Brain -- Cancer -- Diagnosis
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Brain -- Cancer -- Treatment
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Craniopharyngioma -- diagnosis
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Craniopharyngioma -- therapy
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Oncology.
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Neurosurgery.
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Endocrinology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Brain -- Cancer -- Diagnosis
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Brain -- Cancer -- Treatment
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Brain -- Tumors -- Diagnosis
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Brain -- Tumors -- Treatment
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| Form |
Electronic book
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| Author |
Lania, Andrea, editor
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Spada, Anna, editor
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Lasio, Giovanni, editor
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| ISBN |
9783319222974 |
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331922297X |
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3319222961 |
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9783319222967 |
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