| Description |
1 online resource (1 volume) : illustrations |
| Series |
Chapman & Hall/CRC Biostatistics Series |
|
Chapman & Hall/CRC biostatistics series
|
| Contents |
Front Cover; Contents; List of Figures; List of Tables; Preface; Introduction; Chapter 1: Regression Models and Their Analysis; Chapter 2: Convex Design Theory; Chapter 3: Algorithms and Numerical Techniques; Chapter 4: Optimal Design under Constraints; Chapter 5: Nonlinear Response Models; Chapter 6: Locally Optimal Designs in Dose Finding; Chapter 7: Locally Optimal Designs in PK/PD Studies; Chapter 8: Adaptive Model-Based Designs; Chapter 9: Other Applications of Optimal Designs; Chapter 10: Useful Matrix Formulae; Bibliography; Back Cover |
| Summary |
Optimal Design for Nonlinear Response Models discusses the theory and applications of model-based experimental design with a strong emphasis on biopharmaceutical studies. The book draws on the authors' many years of experience in academia and the pharmaceutical industry. While the focus is on nonlinear models, the book begins with an explanation of the key ideas, using linear models as examples. Applying the linearization in the parameter space, it then covers nonlinear models and locally optimal designs as well as minimax, optimal on average, and Bayesian designs. The authors also discuss ada |
| Subject |
Optimal designs (Statistics)
|
|
Regression analysis.
|
|
Nonlinear theories.
|
|
Regression Analysis
|
|
Nonlinear theories
|
|
Optimal designs (Statistics)
|
|
Regression analysis
|
| Form |
Electronic book
|
| Author |
Leonov, Sergei L
|
| ISBN |
1439821526 |
|
9781439821527 |
|
