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Title Human Reproductive and Prenatal Genetics / edited by Peter C.K. Leung and Jie Qiao
Published [Place of publication not identified] : Elsevier Ltd. : Academic Press, 2018
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Description 1 online resource
Contents Intro; Title page; Table of Contents; Copyright; Contributors; Part I: Reproductive Tract Development and Gametogenesis; Chapter 1: Developmental Genetics of the Male Reproductive System; Abstract; Introduction; Early Testicular Development; Testicular Descent; Development of the External Genitalia; Birth Defects; Conclusion; Glossary; Chapter 2: Genetics and Genomics of Early Gonad Development; Abstract; Introduction; Molecular Physiology in Gonad Development; Essential Transcription Factors in Gonad Development; Conclusions; Chapter 3: Genetics of Meiotic Chromosome Dynamics and Fertility
AbstractAcknowledgments; Overview and Scope; Meiosis and Its Regulation in Males and Females; Genetic Approaches to Study Meiosis; Meiotic Prophase Chromosome Dynamics: the Foundation of Meiosis; Meiotic Division Phases: The Culmination of Meiosis; Meiosis, Fertility, and Human Health; Summary and Perspectives; Chapter 4: Effects of Aging on Sperm Chromatin; Abstract; Acknowledgments; Introduction; Transformations of the Nucleus During Spermatogenesis; Aging and Male Germ Cells; Conclusion; Chapter 5: In Vitro Spermatogenesis From Pluripotent Stem Cells; Abstract; Introduction
Biological Significance of the Translation Program in OocytesConclusions and Perspectives; Chapter 10: Translational Regulation of Gene Expression During Oogenesis and Preimplantation Embryo Development; Abstract; Introduction; Factors Determining Oocyte Transcriptome; Essential Regulatory Components of Translation in Somatic Cells; Translation Regulatory Pathways in Oocytes and Early Preimplantation Embryos; Translational Regulation in the Early Embryo; Conclusion; Chapter 11: MicroRNAs in Gametes and Preimplantation Embryos: Clinical Implications; Abstract; Acknowledgments; Introduction
Induction of Spermatogenesis in MiceInduction of Spermatogenesis in Humans; Discussion; Chapter 6: Developmental Genetics of the Female Reproductive Tract; Abstract; Introduction; Embryogenesis of the Female Reproductive Tract; Fallopian Tube Anomalies; Uterine Anomalies; Cervical Anomalies; Development of the Vagina; Conclusion; Chapter 7: The Molecular Genetics of Oogenesis; Abstract; Acknowledgments; Introduction; Oogenesis: An Overview; Nuclear DNA (nDNA) Inheritance; Mitochondrial Inheritance; Summary; Chapter 8: Epigenetic Control of Oocyte Development; Abstract; Acknowledgments
IntroductionEpigenetic Modifications in the Oocyte Genome; Establishment of DNA Methylation During Oocyte Growth; Histone Modifications During Oocyte Growth; Large-Scale Chromatin Remodeling in the Oocyte Genome; Heterochromatin Formation and Chromosome Stability During Oocyte Meiosis; Chromosome-Microtubule Interactions at the Kinetochore; Environmental and Hormonal Causes of Oocyte Aneuploidy; Conclusions; Chapter 9: RNA Binding Protein Networks and Translational Regulation in Oocytes; Abstract; Introduction; Oocyte Meiotic Maturation; Components of the Translational Program in Oocytes
Summary Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available
Notes Online resource; title from PDF file page (EBSCO, viewed September 6, 2018)
Subject Human reproduction
Human reproductive technology
HEALTH & FITNESS / Sexuality.
Human reproduction.
Human reproductive technology.
Form Electronic book
Author Leung, Peter C. K., editor
Qiao, Jie, editor
ISBN 0128135719 (electronic bk.)
9780128135716 (electronic bk.)