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Title Melatonin and melatonergic drugs in clinical practice / Srinivasan Venkataramanujam, Amnon Brzezinski, Sukru Oter, Samuel D. Shillcutt, editors
Published New Delhi : Springer, 2014
Table of Contents
1.Melatonin Receptors and Their Role in Human Diseases / Theresia Thalhammer1
2.Melatonin's Antioxidant Properties: Molecular Mechanisms / Rudiger Hardeland17
3.Past, Present, and Future of Melatonin's Clinical Uses / Agata Rita Carpentieri27
4.Melatonin in Human Cancer: Therapeutic Possibilities / Paolo Lissoni43
5.Melatonin: Its Microbicidal Properties and Clinical Applications / Hisanori Kato57
6.Melatonin and the Metabolic Syndrome / Amanda Lochner71
7.Development of Agonists and Antagonists for Melatonin Receptors / Darius P. Zlotos97
8.Multiple Facets of Melatonin in Immunity: Clinical Applications / Antonio Carrillo-Vico117
9.Melatonin and Immune Function: Clinical Significance / Sukru Oter143
10.Circadian Variation of Immune Mechanisms in Lung Cancer and the Role of Melatonin / Gianluigi Mazzoccoli159
11.Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer / Samuel Cos Corral171
12.Melatonin and Malaria: Therapeutic Avenues / Rozieyati Mohamed Saleh183
13.Melatonin's Role in Human Reproduction: Recent Studies / V. Srinivasan193
14.Melatonin: An Introduction to Its Physiological and Pharmacological Effects in Humans / Bruno Claustrat205
15.Melatonin and Pain: Therapeutic Applications / Edward C. Lauterbach221
16.Melatonin in Alzheimer's Disease: Focus on Neuroprotective Role / Samuel D. Shillcutt235
17.Melatonin in Parkinson's Disease and Its Therapeutic Potential / Dario Acuna-Castroviejo249
18.Melatonin and Its Agonists in Sleep Disorders / Amnon Brzezinski263
19.Agomelatine in Depressive Disorders / Franca M. Placenza275
20.Melatonin in Mood Disorders and Agomelatine's Antidepressant Efficacy / Timo Partonen281
21.The Role of Agomelatine in the Treatment of Anxiety Disorders / Massimo Di Giannantonio297
22.Melatonin in the Etiology, Pathophysiology, and Management of Schizophrenia / Michael Maes307
23.Neurobiology of Monoaminergic Neurotransmission and Antidepressants / Cecilio Alamo321
24.Melatonergic Drug: Ramelteon and Its Therapeutic Applications in Insomnia / Atul Prasad343
25.Melatonin's Neuroprotective Actions on Hippocampal Neurons / Maheep Bhatnagar353
26.Jet Lag: Use of Melatonin and Melatonergic Drugs / Gregory M. Brown367
27.Sleep, Melatonin, and Circadian Rhythmicity in Attention Deficit Hyperactivity Disorder / Marcel G. Smits379
28.Melatonergic Drugs and Their Therapeutic Use in Nasal Polyposis / Onder Karaaslan385
29.Protective Effects of Exogenous Melatonin Against Methotrexate-Induced Intestinal Injury / Bina Isaac389
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Contents Melatonin Receptors and Their Role in Human Diseases -- Melatonins Antioxidant Properties: Molecular Mechanisms -- Past, Present and Future of Melatonins Clinical Uses -- Melatonin in Human Cancer: Therapeutic Possibilities -- Melatonin: Its Microbicidal Properties and Clinical Applications -- Melatonin and the Metabolic Syndrome -- Development of Agonists and Antagonists for Melatonin Receptors -- Multiple Facets of Melatonin in Immunity: Clinical Applications -- Melatonin and Immune Function: Clinical Significance -- Circadian Variation of Immune Mechanisms in Lung Cancer and the Role of Melatonin -- Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer -- Melatonin and Malaria: Therapeutic Avenues -- Melatonin's role in human reproduction: recent studies -- Melatonin Treatment and Fertility -- Melatonin and Pain: Therapeutic Applications -- Melatonin in Alzheimers disease: Focus on Neuroprotective Role -- Melatonin in Parkinsons disease and its Therapeutic Potential -- Melatonin and Its Agonists in Sleep Disorders -- Agomelatine in Depressive Disorders -- Melatonin in Mood Disorders and Agomelatines Antidepressant Efficacy -- The Role of Agomelatine in the Treatment of Anxiety Disorders .- Melatonin in the Etiology, Pathophysiology, and Management of Schizophrenia -- Neurobiology of Monoaminergic Neurotransmission and Antidepressants -- Melatonergic Drug -- Ramelteon and Its Therapeutic Applications in Insomnia -- Melatonins Neuroprotective Actions on Hippocampal Neurons -- Jet Lag: Use of Melatonin and Melatonergic Drugs -- Sleep, Melatonin and Circadian Rhythmicity in Attention Deficit Hyperactivity Disorder -- Melatonergic Drugs and Their Therapeutic Use in Nasal Polyposis -- Protective Effects of Exogenous Melatonin Against Methotrexate- Induced Intestinal Injury
Summary The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This bookcontains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinsons disease, Alzheimers disease. Additionally, melatonins therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonins antioxidant role in Duchennes muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science
Bibliography Includes bibliographical references at the end of each chapters
Notes Print version record
Subject Melatonin -- Physiological aspects.
Melatonin -- Therapeutic use.
Melatonin -- therapeutic use.
Melatonin -- pharmacology.
Form Electronic book
Author Srinivasan, V. (Venkataramanujan), editor
Brzezinski, Amnon, editor
Oter, Sukru, editor
Shillcutt, Samuel D., editor
LC no. 2013956613
ISBN 9788132208259 (electronic bk.)
8132208250 (electronic bk.)
8132208242
9788132208242