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Book Cover
Author Halloran, M. Elizabeth.

Title Design and analysis of vaccine studies / M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner
Published New York : Springer, [2010]
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xviii, 387 pages) : illustrations
Series Statistics for biology and health
Statistics for biology and health.
Contents Overview of vaccine effects and study designs -- Immunology and early phase trials -- Binomial and stochastic transmission models -- R[o] and deterministic models -- Evaluating protective effects of vaccination -- Models of action and time-varying VE[s] -- Further evaluation of protective effects -- Vaccine effects on post-infection outcomes -- Household-based studies -- Analysis of households in communities -- Analysis of independent households -- Assessing indirect, total, and overall effects -- Randomization and baseline transmission -- Surrogates of protection
Bibliography Includes bibliographical references (pages 361-379) and index
Notes Print version record
Subject Vaccines -- Research.
Vaccines -- Statistical methods.
Epidemiology -- Research.
Case-control method.
Research Design.
Clinical Trials as Topic.
Drug Evaluation -- methods.
Research Design.
Statistics as Topic.
Form Electronic book
Author Longini, Ira M.
Struchiner, Claudio J.
LC no. 2009938829
ISBN 0387686363 (e-isbn)
9780387686363 (e-isbn)