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Title Toxins and drug discovery / P. Gopalakrishnakone, editor-in-chief ; Lourdes J. Cruz, Sulan Luo, editors
Published Dordrecht, Netherlands : Springer, 2017

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Description 1 online resource : illustrations (some color)
Series Toxinology, 2542-761X
Toxinology, 2542-761X
Contents Crotoxin from Crotalus durissus terrificus and Crotoxin-Related Proteins: Structure and Function Relationship -- Dexamethasone Antagonizes Myotoxic and Inflammatory Effects Induced by Bothrops Snake Venoms -- Inflammatory Action of Secretory PLA2 from Snake Venoms -- Natural Inhibitors of Snake Venom Metallopeptidases -- Production and Utilization of Snake Antivenoms in South America -- Snake Venom Components as Basis for Biologically Active Synthetic Peptides -- Antiproliferative Effects of Snake Venom Phospholipases A2 and Their Perspectives for Cancer Treatment -- Conotoxins and Drug Discovery with Special Reference to Hainan Species -- Conotoxins as Tools in Research on Nicotinic Receptors -- Random Peptide Library for Ligand and Drug Discovery -- Synthetic Peptides and Drug Discovery -- Bee Venom and Pain -- L-Amino Acid Oxidase from Venoms -- Myotoxin Inhibitors -- Computational Approaches for Animal Toxins to Aid Drug Discovery -- Toad Poison and Drug Discovery -- Venoms as Sources of Novel Anti-parasitic Agents -- Intriguing Cystine-Knot Miniproteins in Drug Design and Therapeutics -- Intriguing Cystine-Knot Miniproteins in Drug Design and Therapeutics
Summary This volume deals mainly with the specialized aspect of toxins and drug discovery. Man has been using natural resources especially plants to treat diseases from very early times in history of mankind. Although many drugs derived from plants and microbes have been discovered and being used in clinical practice, not many drugs have been developed from venoms and toxins although many laboratories worldwide are actively working on it. This volume describe some of the recent developments in this research area, such as snake venoms, conotoxins, bioinformatics in drug discovery from peptide toxins
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed April 19, 2017)
Subject Toxins.
Drug development.
Toxins, Biological
Drug development
Toxins
Form Electronic book
Author Cruz, Lourdes J., editor
Luo, Sulan, editor
Gopalakrishnakone, P., editor.
ISBN 9789400764521
9400764529
9789400764538
9400764537