Molecular Basisof Multiple Sclerosis; Neuro-Immune Crosstalk in CNS Diseases; Role of NK Cells and Invariant NKT Cells in Multiple Sclerosis; Potential Triggers of MS; Prospects for Antigen-Specific Tolerance Based Therapies for the Treatment of Multiple Sclerosis; Immuno-Therapeutic Potential of Haematopoietic and Mesenchymal Stem Cell Transplantation in MS; Immune-Mediated CNS Damage; B Cells and Antibodies in MS; Immunological Basis for the Developmentof Tissue Inflammation and Organ-SpecificAutoimmunity in Animal Modelsof Multiple Sclerosis
Summary
Despite major efforts by the scientific community over the years, our understanding of the pathogenesis or the mechanisms of injury of multiple sclerosis is still limited. Consequently, the current strategies for treatment and management of patients are limited in their efficacy. The mechanisms of tissue protection and repair are probably even less understood. One reason for these limitations is the enormous complexity of the disease and every facet of its pathogenesis, the mechanisms of tissue injury, the diagnostic procedures and finally the efficacy of treatments and their side effects. The