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Title Introduction to basics of pharmacology and toxicology. Volume 2, Essentials of systemic pharmacology : from principles to practice / Abialbon Paul, Nishanthi Anandabaskar, Jayanthi Mathaiyan, Gerard Marshall Raj, editors
Published Singapore : Springer, [2021]

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Description 1 online resource (1156 pages)
Contents Intro -- Foreword -- Preface -- Preface to Volume 1: General and Molecular Pharmacology: Principles of Drug Action (https://link.springer.com/book/10.1007/978 ... -- Acknowledgments -- Contents -- Editors and Contributors -- Part I: Autonomic Nervous System -- 1: Cholinoceptor Agonists and Anticholinesterase Agents -- 1.1 Introduction -- 1.2 Synthesis and Degradation of ACh -- 1.3 Cholinergic Receptors -- 1.4 Action of ACh in Different Organ Systems -- 1.4.1 Central Nervous System -- 1.4.2 Heart -- 1.4.3 Blood Vessels -- 1.4.4 Lungs -- 1.4.5 Gastrointestinal Tract -- 1.4.6 Urinary Tract
1.4.7 Eye -- 1.4.8 Glands -- 1.4.9 Skeletal Muscles -- 1.4.10 Ganglion -- 1.5 Cholinomimetic Drugs -- 1.5.1 Classification -- 1.5.2 Direct Muscarinic Agonists -- 1.5.3 Toxicology of Muscarinic Alkaloids -- 1.5.4 AChE and Anticholinesterases -- 1.5.5 Pharmacological Actions of Anticholinesterases -- 1.5.6 Therapeutic Uses of Anticholinesterases -- 1.6 Toxicology of Anticholinesterases: Management of OPC and Carbamate Poisoning -- 1.6.1 Acute Organophosphorus Poisoning -- 1.6.2 Acute Carbamate Poisoning -- 1.6.3 Intermediate Syndrome in OPC Poisoning -- 1.6.4 Delayed Neuropathy in OPC Poisoning
2.6.5 Bronchial Asthma and COPD -- 2.6.6 Motion Sickness -- 2.6.7 Arrhythmias -- 2.6.8 Drug-Induced Parkinsonism -- 2.6.9 In Poisoning -- 2.6.10 Other Uses with Unproven Efficacy -- 2.7 Adverse Effects and Contraindications -- 2.8 Management of Anticholinergic Poisoning -- 2.9 Ganglion Blockers -- Bibliography -- 3: Adrenergic Agonists -- 3.1 Organ Specific Effects of Adrenergic Agonists -- 3.1.1 Cardiovascular System -- 3.1.1.1 Effect of the Alpha 1 Receptor Activation -- Vascular Tone -- Cardiac Parameters -- Blood Pressure -- 3.1.1.2 Effect of Alpha 2 Receptor Activation -- Peripheral Action
Central Action -- 3.1.1.3 Effect of Beta 1 Receptor Activation -- Cardiac Parameters -- 3.1.1.4 Effect of Beta 2 Receptor Activation -- 3.1.1.5 Effect of Dopamine Receptor Activation -- 3.1.2 Effects on Other Organ Systems (Box 3.1) -- Box 3.1 Effects on Other Organ Systems -- 3.2 Sympathomimetic Drugs -- 3.2.1 Endogenous Catecholamines -- 3.2.1.1 Epinephrine -- Pharmacokinetics -- Mechanisms of Action on Various Organ Systems and Uses of Epinephrine -- Adverse Drug Reactions -- Uses of Epinephrine -- 3.2.1.2 Norepinephrine -- Cardiovascular System -- Adverse Drug Reactions -- Therapeutic Uses
Summary This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences
Notes Print version record
In Springer Nature eBook
Subject Pharmacology.
Pharmacology
pharmacology.
Drug resistance
Neurosciences
Pharmacology
Pharmacy
Vaccines
Form Electronic book
Author Paul, Abialbon, editor
Anandabaskar, Nishanthi, editor
Mathaiyan, Jayanthi, editor
Raj, Gerard Marshall, editor
ISBN 9789813360099
9813360097
Other Titles Essentials of systemic pharmacology : from principles to practice