| Description |
1 online resource (x, 564 pages) : illustrations |
| Contents |
Note continued: 3. Fibrous Scaffolds for Tissue Engineering / Sarah E. Grieshaber / Xinqiao Jia / Alexandra J.E. Farran / Amit K. Jha -- 3.1. Introduction / James A. Cooper Jr. / Wan-Ju Li -- 3.2. Rationale for Using Fibers as a Scaffolding Material / James A. Cooper Jr. / Wan-Ju Li -- 3.2.1. Favorable Structural Properties / James A. Cooper Jr. / Wan-Ju Li -- 3.2.2. Imitation of Extracellular Matrix / James A. Cooper Jr. / Wan-Ju Li -- 3.2.3. Structural and Property Versatility / James A. Cooper Jr. / Wan-Ju Li -- 3.3. Microfibrous Scaffolds / James A. Cooper Jr. / Wan-Ju Li -- 3.3.1. Fabrication / James A. Cooper Jr. / Wan-Ju Li -- 3.3.2. Biomedical Applications / James A. Cooper Jr. / Wan-Ju Li -- 3.4. Nanofibrous Scaffolds / James A. Cooper Jr. / Wan-Ju Li -- 3.4.1. Fabrication / James A. Cooper Jr. / Wan-Ju Li -- 3.5. Electrospinning Technique / James A. Cooper Jr. / Wan-Ju Li -- 3.5.1. Setup / James A. Cooper Jr. / Wan-Ju Li -- 3.5.2. Fabrication and Properties of Electrospun Nanofibrous Scaffolds / James A. Cooper Jr. / Wan-Ju Li -- 3.5.3. Biological Enhancement with Nanofibrous Scaffold / James A. Cooper Jr. / Wan-Ju Li -- 3.5.4. Biomaterials for Nanofibrous Scaffolds / James A. Cooper Jr. / Wan-Ju Li -- 3.5.5. Comparison Between Microfibrous and Nanofibrous Scaffolds / James A. Cooper Jr. / Wan-Ju Li -- 3.5.6. Nanofibrous Scaffolds for Tissue Engineering Applications / James A. Cooper Jr. / Wan-Ju Li -- 3.6. Future Directions / James A. Cooper Jr. / Wan-Ju Li -- References / James A. Cooper Jr. / Wan-Ju Li -- 4. Bioelastomers in Tissue Engineering / James A. Cooper Jr. / Wan-Ju Li -- 4.1. Introduction / Yadong Wang / Zhengwei You -- 4.1.1. Matrix Elasticity Impacts Cell and Tissue Function / Yadong Wang / Zhengwei You -- 4.1.2. Mechanical Stimulation Affects Cell and Tissue Development / Yadong Wang / Zhengwei You |
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Note continued: 4.1.3. Elastic Materials are Important Scaffold Materials for Tissue Engineering / Yadong Wang / Zhengwei You -- 4.2. Designing Bioelastomers for Tissue Engineering / Yadong Wang / Zhengwei You -- 4.2.1. Important Considerations in Bioelastomer Design / Yadong Wang / Zhengwei You -- 4.2.2. Current State of Bioelastomers / Yadong Wang / Zhengwei You -- 4.3. Recent Progress of Synthetic Bioelastomers / Yadong Wang / Zhengwei You -- 4.3.1. Polyurethanes / Yadong Wang / Zhengwei You -- 4.3.2. Other Thermoplastic Bioelastomers / Yadong Wang / Zhengwei You -- 4.3.3. Poly(glycerol sebacate) / Yadong Wang / Zhengwei You -- 4.3.4. Other Thermoset Bioelastomers / Yadong Wang / Zhengwei You -- 4.4. Future Directions / Yadong Wang / Zhengwei You -- References / Yadong Wang / Zhengwei You -- 5. Microscale Biomaterials for Tissue Engineering / Yadong Wang / Zhengwei You -- 5.1. Introduction / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.2. Microscale Technologies for Engineering Biomaterials and the Cell Microenvironment / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.2.1. Photolithography / Ian Wheeldon / Javier Fernandez / Hojae Bae / Hirokazu Kaji / Ali Khademhosseini -- 5.2.2. Soft Lithography / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.2.3. Microfluidics / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.2.4. Robotic Spotting and Printing / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.2.5. Other Microscale Techniques / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae |
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Note continued: 5.3. Microscale Engineering of the Cell Microenvironment / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.3.1. Cell Patterning and Controlling Cell[-]Cell Contacts / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.3.2. Controlling Tissue Microarchitecture / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.3.3. Cell-Soluble Factor Interactions / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.4. High Thoughput and Combinatorial Investigations of the Cell Microenvironment / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.4.1. High Throughput Synthesis and Screening of Cell Microenvironments / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.4.2. Microfluidics for High Throughput Investigations of the Cell Microenvironment / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 5.5. Future Directions / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- References / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 6. Micro and Nanotechnologies for Tissue Engineering / Ian Wheeldon / Javier Fernandez / Ali Khademhosseini / Hirokazu Kaji / Hojae Bae -- 6.1. Introduction / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.2. Creation of Micro- and Nano Features on 2D Substrates / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.2.1. Substrate Modification / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.2.2. Surface Patterning / Nadeen O. Chahine / Pen-hsiu Grace Chao -- 6.2.3. Soft Lithography / Pen-hsiu Grace Chao / Nadeen O. Chahine |
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Note continued: 6.2.4. Micro Contact Printing ([æ]CP) / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.2.5. Micro and Nano Fluidics / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3. Cellular Interactions with 2D Micro and Nano Patterns / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3.1. Mechanism of Cell[-]Matrix Interactions / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3.2. Changes in Morphology / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3.3. Effect on Migration / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3.4. Cellular Proliferation / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.3.5. Phenotype / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.4. Nanomaterials and Synthesis / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.4.1. Nanofibers / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.4.2. Nanotubes / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.4.3. Functionalized Nanomaterials / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5. Interfacing Cells with Nanomaterials / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5.1. Bone Tissue Engineering / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5.2. Articular Cartilage Tissue Engineering / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5.3. Fibrocartilaginous Tissues (Meniscus and Intervertebral Disc) / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5.4. Tendon/Ligament Tissue Engineering / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.5.5. Neural and Muscular Tissue Engineering / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 6.6. Future Directions / Pen-hsiu Grace Chao / Nadeen O. Chahine -- References / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 7. Bioceramics in Tissue Engineering / Pen-hsiu Grace Chao / Nadeen O. Chahine -- 7.1. Introduction / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park |
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Note continued: 7.2. Classification of Bioceramics / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.2.1. Bioinert Ceramics / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.2.2. Glass-Ceramic and Bioactive Glass / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.2.3. Calcium Phosphate Bioceramics / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.3. Applications of Calcium Phosphate Ceramics / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.3.1. Bioactive Cement / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.3.2. Porous Bioceramic Scaffolds for Bone Tissue Engineering / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.3.3. Ceramic-Based Composite Scaffold for Tissue Engineering and Drug Delivery / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.4. Bioceramics for Cancer Therapy / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.4.1. Bioceramics for Radiation Therapy / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.4.2. Bioceramics for Hyperthermia Therapy for Cancer / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.5. Bioceramics for Dental Application / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 7.6. Future Trends / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- References / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 8. Natural Materials in Tissue Engineering Applications / Yunzhi Yang / Yunqing Kang / Milan Sen / Sangwon Park -- 8.1. Introduction / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2. Concepts in Material Development / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters |
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Note continued: 8.2.1. Collagen and Gelatin / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.2. Fibrin / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.3. Elastin / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.4. Hyaluronic Acid / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.5. Silk / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.6. Alginate / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.2.7. Chitosan / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.3. Review of Previous Work / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.3.1. Collagen and Gelatin / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters -- 8.3.2. Fibrin / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Kristyn S. Masters / Xiaoxiao Gu -- 8.3.3. Silk / Chloe M. McCoy / Karien J. Rodriguez / Elyssa L. Monzack / Xiaoxiao Gu / Kristyn S. Masters -- 8.3.4. Elastin / Kristyn S. Masters / Xiaoxiao Gu / Chloe M. McCoy / Karien J. Rodriguez / Elyssa L. Monzack -- 8.3.5. Hyaluronic Acid / Kristyn S. Masters / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu -- 8.3.6. Alginate / Karien J. Rodriguez / Kristyn S. Masters / Xiaoxiao Gu / Chloe M. McCoy / Elyssa L. Monzack -- 8.3.7. Chitosan / Karien J. Rodriguez / Elyssa L. Monzack / Xiaoxiao Gu / Chloe M. McCoy / Kristyn S. Masters |
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Note continued: 8.4. Future Directions / Kristyn S. Masters / Chloe M. McCoy / Elyssa L. Monzack / Karien J. Rodriguez / Xiaoxiao Gu -- References / Elyssa L. Monzack / Chloe M. McCoy / Xiaoxiao Gu / Kristyn S. Masters / Karien J. Rodriguez -- 9. Engineered Polypeptides for Tissue Engineering / Kristyn S. Masters / Elyssa L. Monzack / Karien J. Rodriguez / Chloe M. McCoy / Xiaoxiao Gu -- 9.1. Introduction / Wei Shen -- 9.2. Concepts in Material Development / Wei Shen -- 9.3. Review of Previous Work / Wei Shen -- 9.3.1. Collagen-Inspired Polypeptide Materials / Wei Shen -- 9.3.2. Elastin-Inspired Polypeptide Materials 25I / Wei Shen -- 9.3.3. Silk-Inspired Polypeptide Materials / Wei Shen -- 9.3.4. Polypeptide Materials Self-Assembled Through & alpha;-Helical Domains / Wei Shen -- 9.3.5. Bioactive and Dynamic Materials / Wei Shen -- 9.3.6. Biosynthetic Incorporation of Non-natural Amino Acid Analogs for Engineering Polypeptide Materials / Wei Shen -- 9.4. Future Directions / Wei Shen -- References / Wei Shen -- 10. Cartilage Engineering: Current Status and Future Trends / Wei Shen -- 10.1. Cartilage Tissue: Structure, Function, and Disease / Emily E. Coates / John P. Fisher -- 10.1.1. Cellular and Extracellular Matrix Components / Emily E. Coates / John P. Fisher -- 10.1.2. Proper Tissue Function and Response to Stress / Emily E. Coates / John P. Fisher -- 10.1.3. Aged and Damaged Tissue / Emily E. Coates / John P. Fisher -- 10.1.4. Need for Repair and Regeneration Strategies / Emily E. Coates / John P. Fisher -- 10.2. Current Standards of Care and Limitations / Emily E. Coates / John P. Fisher -- 10.2.1. Current Treatments in Cartilage Repair / Emily E. Coates / John P. Fisher -- 10.2.2. Limitations of Current Standard Practices and Need for Engineering Approaches / Emily E. Coates / John P. Fisher |
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Note continued: 10.3. Cartilage Engineering / Emily E. Coates / John P. Fisher -- 10.3.1. Requirements of an Engineered Construct / Emily E. Coates / John P. Fisher -- 10.3.2. Biomaterials and Cells for Cartilage Engineering / Emily E. Coates / John P. Fisher -- 10.3.3. Engineered Constructs in Clinical Trials and Early Applications / Emily E. Coates / John P. Fisher -- 10.3.4. Current Research Efforts / Emily E. Coates / John P. Fisher -- 10.4. Future Directions / Emily E. Coates / John P. Fisher -- 10.4.1. Zonal Cartilage Engineering / Emily E. Coates / John P. Fisher -- 10.4.2. Stem Cells / Emily E. Coates / John P. Fisher -- 10.4.3. Dynamic Culture Systems / Emily E. Coates / John P. Fisher -- References / Emily E. Coates / John P. Fisher -- 11. Biomaterials for Regeneration of Tendons and Ligaments / Emily E. Coates / John P. Fisher -- 11.1. Introduction / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.2. Tissue Overview and Requirements / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.2.1. Physiology and Mechanical Properties / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.2.2. Structure 31I / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.2.3. Interfaces with Other Orthopaedic Tissues / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.2.4. Injury and Repair / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.3. Current Techniques for Reconstruction and Tissue Engineering / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.3.1. Current Surgical Management and Reconstruction of Tendons and Ligaments / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.3.2. Biomaterials for Tissue Engineering of Tendons and Ligaments / Taymour M. Hammoudi / Johnna S. Temenoff -- 11.4. Conclusions and Future Work / Taymour M. Hammoudi / Johnna S. Temenoff -- References / Johnna S. Temenoff / Taymour M. Hammoudi |
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Note continued: 12. Materials for Bone Graft Substitutes and Osseous Tissue Regeneration / Taymour M. Hammoudi / Johnna S. Temenoff -- 12.1. Introduction / Steven B. Nicoll -- 12.2. Current Bone Grafting Materials / Steven B. Nicoll -- 12.2.1. Demineralized Bone Matrix / Steven B. Nicoll -- 12.2.2. Calcium Phosphate Ceramics and Bioactive Glasses / Steven B. Nicoll -- 12.2.3. Natural and Synthetic Polymers / Steven B. Nicoll -- 12.3. New Developments in Bone Grafting Materials / Steven B. Nicoll -- 12.3.1. Self-Assembled Biomimetic Materials / Steven B. Nicoll -- 12.3.2. Nanocomposite Scaffolds (Collagen) / Steven B. Nicoll -- 12.3.3. Nanocomposite Scaffolds (Synthetics) / Steven B. Nicoll -- 12.3.4. Nanocomposite Scaffolds (Natural Materials) / Steven B. Nicoll -- 12.3.5. Microsphere-Based Scaffolds / Steven B. Nicoll -- 12.3.6. Nanophase Ceramics and Material Properties/Processing / Steven B. Nicoll -- 12.4. Future Directions / Steven B. Nicoll -- References / Steven B. Nicoll -- 13. Fibrocartilage Tissue Engineering / Steven B. Nicoll -- 13.1. Introduction / Christopher J. Hunter -- 13.2. Tissue Overview/Requirements / Christopher J. Hunter -- 13.3. Review of Previous Work / Christopher J. Hunter -- 13.3.1. Architecture / Christopher J. Hunter -- 13.3.2. Biocompatibility / Christopher J. Hunter -- 13.3.3. Bioactive Cues / Christopher J. Hunter -- 13.3.4. Mechanical Function / Christopher J. Hunter -- 13.3.5. Deliverability / Christopher J. Hunter -- 13.4. Future Directions / Christopher J. Hunter -- 13.4.1. Aligned/Microengineered Anisotropic Materials / Christopher J. Hunter -- 13.4.2. Cell Adhesion and Targeted Signalling / Christopher J. Hunter -- 13.4.3. Delivery Systems / Christopher J. Hunter -- 13.4.4. Ultimate Engineered Fibrocartilage: One Author's Guess / Christopher J. Hunter -- References / Christopher J. Hunter |
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Note continued: 14. Liver Tissue Engineering / Christopher J. Hunter -- 14.1. Introduction / Deepak Nagrath / Sihong Wang -- 14.2. Concepts in Liver Tissue Engineering / Deepak Nagrath / Sihong Wang -- 14.2.1. Liver Anatomy, Physiology and Diseases / Deepak Nagrath / Sihong Wang -- 14.2.2. Cell Source for Liver Tissue Engineering / Deepak Nagrath / Sihong Wang -- 14.2.3. Methods and Biomaterials for Ex Vivo Primary Hepatocyte Culture / Deepak Nagrath / Sihong Wang -- 14.3. Review of Previous Work of Liver Support Systems / Deepak Nagrath / Sihong Wang -- 14.3.1. Artificial/Bioartificial Liver / Deepak Nagrath / Sihong Wang -- 14.3.2. Hepatocyte Transplantation and Transplantable Liver Constructs / Deepak Nagrath / Sihong Wang -- 14.4. Future Directions / Deepak Nagrath / Sihong Wang -- References / Deepak Nagrath / Sihong Wang -- 15. Cardiac Tissue Engineering / Deepak Nagrath / Sihong Wang -- 15.1. Introduction / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.2. Cardiac Tissue Overview and Requirements for Successful Tissue Engineering / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.2.1. Healthy Myocardium / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.2.2. Myocardial Infarction and Heart Failure / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.2.3. Current Clinical Treatment Methods / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.2.4. Emerging Treatment Options / Loraine Chiu / Lewis Reis / Devang Odedra / Katherine Chiang / Milica Radisic / Fiona Rask |
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Note continued: 15.2.5. Requirements for Successful Myocardial Regeneration / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.3. Review of Previous Work / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.3.1. Cell Injection / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.3.2. In Vitro Cardiac Tissue Engineering / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.4. Future Directions / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 15.5. Summary / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- References / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 16. Biomaterials Approaches in Vascular Engineering: a Review of Past and Future Trends / Devang Odedra / Loraine Chiu / Milica Radisic / Fiona Rask / Katherine Chiang / Lewis Reis -- 16.1. Introduction / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.1.1. Importance of Vascularization / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.1.2. Cell Sources / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.1.3. Angiogenic Growth Factors / Sharon Gerecht / Maureen Wanjare / Donny Hanjaya-Putra -- 16.1.4. Scaffold Design / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.2. Concepts in Material Development and Tissue Requirements / Donny Hanjaya-Putra / Maureen Wanjare / Sharon Gerecht -- 16.2.1. Biomimetic Materials: A Lesson from Postnatal Angiogenesis / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.2.2. Natural and Synthetic Biomaterials / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare |
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Note continued: 16.2.3. Cell Adhesion Regulates Vacuole Formation / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.2.4. Cell-Mediated Degradation Allows Lumen Formation / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.2.5. GFs and Oxygen Tension / Sharon Gerecht / Maureen Wanjare / Donny Hanjaya-Putra -- 16.2.6. Tube Stabilization by Prevascular Cells / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.2.7. Biomechanical Control Over Vascular Morphogenesis / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.3. Review of Previous Work / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.3.1. Hydrogels to Control Vascular Differentiation / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.3.2. Biomaterials for GFs and Gene Delivery / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.3.3. Biomaterials for Inducing Prevascularization / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.3.4. Microfabrication of Vascular Networks / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 16.4. Future Directions / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- References / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 17. Neural Tissue Engineering / Donny Hanjaya-Putra / Sharon Gerecht / Maureen Wanjare -- 17.1. Introduction / Erin Lavik -- 17.2. Tissues in Question and How They are Damaged / Erin Lavik -- 17.3. Technologies in Clinical Use and in Clinical Trials / Erin Lavik -- 17.3.1. Nerve Grafts: Autografts and Allografts / Erin Lavik -- 17.3.2. Decellularized Nerve grafts / Erin Lavik -- 17.3.3. Tubes and Conduits / Erin Lavik -- 17.3.4. Cellular Therapies / Erin Lavik -- 17.3.5. Pharmacological Therapies / Erin Lavik -- 17.4. Neural Tissue Engineering / Erin Lavik |
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Note continued: 17.4.1. Early Approaches: Leveraging the Regeneration Seen in the PNS / Erin Lavik -- 17.4.2. Leveraging the Regeneration Seen in the Neonate to Promote Repair in the Adult / Erin Lavik -- 17.4.3. Polymers for SCI More Broadly / Erin Lavik -- 17.5. Future Directions / Erin Lavik -- 17.5.1. Role of Collaborations in Achieving These Goals / Erin Lavik -- 17.6. What We Have Not Covered / Erin Lavik -- References / Erin Lavik -- 18. Controlling Stem Cells with Biomaterials / Erin Lavik -- 18.1. Introduction / Shyni Varghese / Nivedita Sangaj -- 18.2. Biochemical Cues / Shyni Varghese / Nivedita Sangaj -- 18.2.1. ECM-Derived Biomaterials / Shyni Varghese / Nivedita Sangaj -- 18.2.2. Natural Polymers / Shyni Varghese / Nivedita Sangaj -- 18.2.3. Hybrid Materials / Shyni Varghese / Nivedita Sangaj -- 18.2.4. Functionalization with Biochemical Cues / Shyni Varghese / Nivedita Sangaj -- 18.2.5. Synthetic Biomaterials / Shyni Varghese / Nivedita Sangaj -- 18.2.6. Biomaterials as a Reservoir of Growth Factors / Shyni Varghese / Nivedita Sangaj -- 18.2.7. Biomaterials for Immunomodulation / Shyni Varghese / Nivedita Sangaj -- 18.3. Biophysical Cues / Shyni Varghese / Nivedita Sangaj -- 18.3.1. Mechanical Properties of Biomaterials / Shyni Varghese / Nivedita Sangaj -- 18.3.2. Biomaterials for Micro- and Nano-Scale Cues / Shyni Varghese / Nivedita Sangaj -- 18.4. Two-Dimensional Cultures Versus Three-Dimensional Cultures / Shyni Varghese / Nivedita Sangaj -- 18.5. Conclusion and Future Directions / Shyni Varghese / Nivedita Sangaj -- References / Shyni Varghese / Nivedita Sangaj -- 19. Translation of New Tissue Engineering Materials to Clinical Application / Shyni Varghese / Nivedita Sangaj -- 19.1. Introduction / Dolores Baksh / Benjamin A. Byers |
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Note continued: 19.2. Conceptualization and Preclinical Activities / Dolores Baksh / Benjamin A. Byers -- 19.3. Development and Design Control: Engineering Rigor and Quality Systems Implementation / Dolores Baksh / Benjamin A. Byers -- 19.3.1. Applying Design Controls / Dolores Baksh / Benjamin A. Byers -- 19.3.2. Design and Development Planning / Dolores Baksh / Benjamin A. Byers -- 19.3.3. Design Inputs / Dolores Baksh / Benjamin A. Byers -- 19.3.4. Design Outputs / Dolores Baksh / Benjamin A. Byers -- 19.3.5. Design Review / Dolores Baksh / Benjamin A. Byers -- 19.3.6. Design Verification / Dolores Baksh / Benjamin A. Byers -- 19.3.7. Design Validation / Dolores Baksh / Benjamin A. Byers -- 19.3.8. Design Transfer / Benjamin A. Byers / Dolores Baksh -- 19.3.9. Design Changes / Dolores Baksh / Benjamin A. Byers -- 19.3.10. Design History File / Dolores Baksh / Benjamin A. Byers -- 19.4. Regulatory Strategy and Evidence Generation / Benjamin A. Byers / Dolores Baksh -- 19.5. Marketing, Commercialization and Post-market Surveillance / Benjamin A. Byers / Dolores Baksh -- References / Benjamin A. Byers / Dolores Baksh |
| Summary |
"A concise overview of tissue engineering technologies and materials towards specific applications, both past and potential growth areas in this unique discipline is provided to the reader. The specific area of the biomaterial component used within the paradigm of tissue engineering is examined in detail. This is the first work to specifically covers topics of interest with regards to the biomaterial component. The book is divided into 2 sections: general materials technology (e.g., fibrous tissue scaffolds) and applications in the engineering of specific tissues (e.g., materials for cartilage tissue engineering). Each chapter covers the fundamentals and reflects not only a review of the literature, but also addresses the future of the topic. The book is intended for an audience of researchers in both industry and academia that are interested in a concise overview regarding the biomaterials component of tissue engineering, a topic that is timely and only growing as a field."--EBL book details |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Tissue engineering.
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Biomedical materials.
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Cartilage.
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Nanotechnology.
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Tissue scaffolds.
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Nanomedicine.
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Biocompatible Materials
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Cartilage
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Nanomedicine
|
|
Tissue Engineering
|
|
Tissue Scaffolds
|
|
Nanotechnology
|
|
MEDICAL -- Physiology.
|
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SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
|
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Tissue scaffolds
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Nanotechnology
|
|
Cartilage
|
|
Biomedical materials
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|
Tissue engineering
|
| Form |
Electronic book
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| Author |
Burdick, Jason A
|
|
Mauck, Robert L
|
| ISBN |
9783709103852 |
|
3709103851 |
|
3709103843 |
|
9783709103845 |
