| Description |
1 online resource (1 PDF file (xxv, 521 pages)) : illustrations |
| Contents |
Effector and memory T cell responses to commensal bacteria -- What are the consequences of the disappearing human microbiota? -- Pathways in microbe-induced obesity -- Microbial exposure during early life has persistent effects on natural killer T cell function -- The application of ecological theory toward an understanding of the human microbiome -- Seasonal restructuring of the ground squirrel gut microbiota over the annual hibernation cycle -- Lessons from studying insect symbioses -- A new vision of immunity: homeostasis of the superorganism -- Host defense and immunomodulation of mucosal candidiasis -- Microbiota-targeted therapies: an ecological perspective -- Community ecology and the vaginal microbiome -- Investigating bacterial-animal symbioses with light sheet microscopy -- Clinical application of fecal microbiota transplantation in Clostridium difficile infection and beyond -- Consumption of human milk glycoconjugates by infant-associated Bifidobacteria: mechanisms and implications -- Bacteriophage adhering to mucus provide a non-host-derived immunity -- Topographic diversity of fungal and bacterial communities in human skin -- Distinct microbial communities within the endosphere and rhizosphere of Populus deltoides roots across contrasting soil types -- Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis -- Metagenomics and personalized medicine -- From genetics of inflammatory bowel disease towards mechanistic insights -- Antimicrobial peptides and the microbiome |
| Summary |
Individually and collectively, resident microbes play important roles in host health and survival. Shaping and shaped by their host environments, these microorganisms form intricate communities that are in a state of dynamic equilibrium. This ecologic and dynamic view of host-microbe interactions is rapidly redefining our view of health and disease. It is now accepted that the vast majority of microbes are, for the most part, not intrinsically harmful, but rather become established as persistent, co-adapted colonists in equilibrium with their environment, providing useful goods and services to their hosts while deriving benefits from these host associations. Disruption of such alliances may have consequences for host health, and investigations in a wide variety of organisms have begun to illuminate the complex and dynamic network of interaction - across the spectrum of hosts, microbes, and environmental niches - that influence the formation, function, and stability of host-associated microbial communities. Microbial Ecology in States of Health and Disease is the summary of a workshop convened by the Institute of Medicine's Forum on Microbial Threats in March 2013 to explore the scientific and therapeutic implications of microbial ecology in states of health and disease. Participants explored host-microbe interactions in humans, animals, and plants; emerging insights into how microbes may influence the development and maintenance of states of health and disease; the effects of environmental change(s) on the formation, function, and stability of microbial communities; and research challenges and opportunities for this emerging field of inquiry |
| Notes |
Title from PDF title page |
| Bibliography |
Includes bibliographical references |
| Notes |
Financial support for this activity was provided by the U.S. Department of Health and Human Services: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Centers for Disease Control and Prevention, Food and Drug Administration, and the Fogarty International Center; U.S. Department of Defense: Armed Forces Health Surveillance Center, Defense Threat Reduction Agency, and Medical Research and Materiel Command; U.S. Department of Justice: Federal Bureau of Investigation; U.S. Department of Veterans Affairs; U.S. Department of Homeland Security; U.S. Agency for International Development; Uniformed Services University of the Health Sciences; Alfred P. Sloan Foundation; American Society for Microbiology; Burroughs Wellcome Fund; GlaxoSmithKline; Infectious Diseases Society of America; Johnson & Johnson; Merck Company Foundation; and sanofi pasteur. The views presented in this publication do not necessarily reflect the views of the organizations or agencies that provided support for this activity |
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Online resource (viewed on May 16, 2014) |
| Subject |
Microbial ecology -- Health aspects -- Congresses
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Microorganisms -- Research -- Congresses
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Host-bacteria relationships -- Congresses
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Health -- Congresses
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Microbiota
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Host-Pathogen Interactions
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Intestines -- microbiology
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Microbial Interactions
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Microbiological Phenomena
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SCIENCE -- Life Sciences -- Biology.
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SCIENCE -- Life Sciences -- Microbiology.
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Health
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Host-bacteria relationships
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Microorganisms -- Research
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| Genre/Form |
proceedings (reports)
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Conference papers and proceedings
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Conference papers and proceedings.
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Actes de congrès.
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| Form |
Electronic book
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| Author |
Olsen, LeighAnne, author.
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Mack, Alison, author.
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Institute of Medicine (U.S.). Forum on Microbial Threats, issuing body.
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Microbial Ecology in States of Health and Disease (Workshop) (2013 : Washington, D.C.)
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| ISBN |
9780309290623 |
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0309290627 |
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9780309290630 |
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0309290635 |
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