Title Molecular parameters indicating adaptation to mechanical stress in fibrous connective tissue / S. Milz, M. Benjamin, R. Putz

Published Berlin ; New York : Springer, ©2005

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Description 1 online resource (vi, 74 pages) : illustrations Series Advances in anatomy, embryology, and cell biology, 0301-5556 ; 178 Advances in anatomy, embryology, and cell biology ; 178. 0301-5556 Contents Introduction; Aim of the Study; Anatomical Structures Investigated; Materials and Methods; Results; Discussion; Summary Summary "The present study pursues the hypothesis that local compressive force and the occurrence of cartilage-specific transformation processes within tendons and ligaments are directly correlated." "In selected anatomical samples of human origin the distribution pattern of certain components of the extracellular matrix is assessed. Investigations are carried out at the extensor tendons of toes and fingers, at the transverse ligament of the atlas, at the transverse ligament of the acetabulum, and at the tendon of the superior oblique muscle and its trochlea. The molecular components of the extracellular matrix are detected with standardized immunohistochemical methods." "The results show that certain molecules only occur due to compressive stress, others due to tensile stress. The molecular spectrum of the extracellular matrix allows qualifying conclusions to the mechanical situation of a given part of the tissue." "The spatial expansion of the fibrocartilaginous adaptation zones in tendons and ligaments roughly corresponds with the zones subjected to compressive force; tensile stress alone does not result in a production of fibrocartilage."--Jacket Bibliography Includes bibliographical references (pages 63-71) and index In Springer e-books Subject Connective tissues -- Mechanical properties Extracellular matrix. Connective Tissue -- physiology Extracellular Matrix Stress, Mechanical SCIENCE -- Life Sciences -- Anatomy & Physiology. Connective Tissue -- physiology. Extracellular Matrix. Stress, Mechanical. Connective tissues -- Mechanical properties. Biomédecine. Sciences de la vie. Extracellular matrix medicines (material) Genre/Form Electronic books Form Electronic book Author Benjamin, M. (Michael), 1948- Putz, Reinhard ISBN 9783540244745 3540244743 354027832X 9783540278320 1280306343 9781280306341 6610306346 9786610306343

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