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Title Oxidative stress in aging : from model systems to human diseases / edited by Satomi Miwa, Kenneth B. Beckman, Florian L. Muller
Edition First edition
Published New York : Springer, 2008
Online access available from:
Springer eBooks    View Resource Record  


Description 1 online resource (xiii, 320 pages) : illustrations
Series Aging medicine
Aging medicine.
Contents Introduction; The Basics of Oxidative Biochemistry; Retrograde Response, Oxidative Stress, and Cellular Senescence; Reactive Oxygen Species in Molecular Pathways Controlling Aging in the Filamentous Fungus Podospora anserina; Oxidative Stress and Aging in the Budding Yeast Saccharomyces cerevisiae; Oxidative Stress and Aging in the Nematode; Roles of Oxidative Stress in the Aging Process of Drosophila melanogaster; Does Oxidative Stress Limit Mouse Life Span?; Mitochondrial Free Radical Production and Caloric Restriction: Implications in Vertebrate Longevity and Aging; Deregulation of Mitochondrial Function: A Potential Common Theme for Cardiovascular Disease DevelopmentOxidative Stress in Type 2 Diabetes Mellitus; DNA Oxidative Damage and Cancer; Oxidative Stress in Hypertension; Aging and Cardiac Ischemia--Mitochondria and Free Radical Considerations; Role of the Antioxidant Network in the Prevention of Age-Related Diseases; Reactive Oxygen Species as Signaling Molecules; Summary and Outlook
Summary Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not bee
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Aging -- Physiological aspects.
Oxidative stress -- Pathophysiology.
Form Electronic book
Author Beckman, Kenneth B. (Kenneth Bruce)
Miwa, Satomi.
Muller, Florian L.
LC no. 2007942719
ISBN 1588299910