Description |
1 online resource (streaming video file) (866 secs.) |
Series |
Biology |
Summary |
This paper presents a sensitive method called Circle-Seq for purifying extrachromosomal circular DNA (eccDNA). The method encompasses column purification, removal of remaining linear chromosomal DNA, rolling-circle amplification and high-throughput sequencing. Circle-Seq is applicable to genome-scale screening of eukaryotic eccDNA and studying genome instability and copy-number variation |
Audience |
For undergraduate, graduate, and professional students |
Notes |
English |
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Description based on online resource; title from resource description page |
Subject |
Biology
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Form |
Streaming audio
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