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Book Cover
E-book
Author Rehm, Bernd H. A

Title Biopolymers for Biomedical and Biotechnological Applications
Published Newark : John Wiley & Sons, Incorporated, 2021

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Description 1 online resource (403 p.)
Series Advanced Biotechnology Ser
Advanced Biotechnology Ser
Contents Cover -- Title Page -- Copyright -- Contents -- Chapter 1 Advances in Biocompatibility: A Prerequisite for Biomedical Application of Biopolymers -- 1.1 Introduction -- 1.2 Biocompatibility Evaluation of Biopolymeric Materials and Devices -- 1.3 Using a Risk-Based Approach to Biocompatibility -- 1.3.1 Chemistry of Biopolymers and Risk -- 1.3.2 Chemistry Screening of Biopolymers -- 1.4 Specific Biological Endpoint Evaluations -- 1.4.1 Cytotoxicity -- 1.4.2 Systemic Toxicity (Acute, Subacute, Subchronic, and Chronic) -- 1.4.3 Implantation -- 1.5 Conclusion -- References
Chapter 2 Advanced Microbial Polysaccharides -- 2.1 Introduction -- 2.2 Functional Properties and Applications of Microbial Polysaccharides -- 2.3 Commercially Relevant Microbial Polysaccharides: Established Uses and Novel/Prospective Applications -- 2.3.1 Pullulan -- 2.3.2 Scleroglucan -- 2.3.3 Xanthan Gum -- 2.3.4 Dextrans -- 2.3.5 Curdlan -- 2.3.6 Gellan Gum -- 2.3.7 Levan -- 2.3.8 Hyaluronic Acid -- 2.4 Hydrogels Based on Microbial Polysaccharides -- 2.5 Bionanocomposites Based on Microbial Polysaccharides -- 2.6 Bioactive Polysaccharides from Microalgae: An Emerging Area
2.6.1 Polysaccharide-Producing Microalgae -- 2.6.2 Biological Activity and Potential Applications -- 2.6.2.1 Antiviral Activity -- 2.6.2.2 Immunomodulatory, Anti-inflammatory, and Anticancer Activities -- 2.6.2.3 Anticoagulant and Antithrombotic Activity -- 2.6.2.4 Antioxidant Activity -- 2.6.2.5 Other Biological Properties -- 2.6.3 Commercialization Prospects -- 2.7 Applications of Chitinous Polymers -- 2.7.1 Chitin, Chitosan, and Chitinous Polysaccharides -- 2.7.2 Properties of Chitinous Polysaccharides -- 2.7.3 Applications of Chitinous Polysaccharides -- 2.7.3.1 Biomedical Applications
2.7.3.2 Pharmaceutical Applications -- 2.7.3.3 Food Applications -- 2.7.3.4 Other Applications -- 2.8 Microbial Polysaccharides: A World of Opportunities -- Acknowledgments -- References -- Chapter 3 Microbial Cell Factories for Biomanufacturing of Polysaccharides -- 3.1 Introduction -- 3.2 Prominent Microbial Polysaccharides and Their Properties and Applications -- 3.2.1 Xanthan and Acetan -- 3.2.2 Succinoglycan and Galactoglucan -- 3.2.3 Sphingan Polysaccharides -- 3.2.4 Pullulan -- 3.2.5 Cellulose and Curdlan -- 3.2.6 Alginates -- 3.2.7 Hyaluronic Acid or Hyaluronate -- 3.2.8 Dextrans
3.2.9 Levan and Inulin -- 3.3 Biosynthesis Pathways of Bacterial Polysaccharides -- 3.3.1 Genetic Background Required for Biosynthesis of Polysaccharides in Bacteria -- 3.3.2 Production of Active Precursor, Polymerization, and Polysaccharide Modifications -- 3.3.3 Regulatory Pathways and Posttranslational Modifications -- 3.4 Strategies for Engineering Cell Factories -- 3.4.1 Enhancement of Productivity upon the Energetic State of the Cell and Metabolites -- 3.4.2 Genetic and Metabolic Engineering of Cell Factories -- 3.4.3 Strategies for Optimizing Physicochemical Properties of Polysaccharides
Notes Description based upon print version of record
3.4.4 Recombinant Production of Polysaccharides and Tailor-Made Products
Form Electronic book
Author Moradali, M. Fata
ISBN 9783527818303
3527818308