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Title Lentigo maligna melanoma : challenges in diagnosis and management / Kishwer S. Nehal, Klaus J. Busam, editors
Published Cham : Springer, 2017
Online access available from:
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Description 1 online resource (223 pages)
Contents Foreword; Acknowledgments; Contents; Contributors; Part I: Introduction; Chapter 1: Introduction; Chapter 2: Epidemiology and Natural History; Introduction; Incidence; Risk Factors; Progression of LM to LMM; Role of Genetics; Future Direction; Conclusion; References; Part II: Clinical and Pathologic Diagnosis; Chapter 3: Clinical Diagnosis; Introduction; Clinical Diagnosis; Patient Demographics; Location; Size; Morphology (Borders and Colors); ABCDE's of Melanoma; Deciding Whether and How to Biopsy; Wood's Lamp; Biopsy Techniques; Sampling Error; Conclusion; References
Advantages and Disadvantages of Staged Excision Techniques Conclusion; References; Chapter 7: Mohs Surgery for Lentigo Maligna Melanoma; Introduction; History of Mohs Micrographic Surgery; The Process of Mohs Micrographic Surgery for Melanoma; Tumor Debulking for Melanoma Pathologic Staging; Immunohistochemical Stains for Melanoma; Highly Skilled Mohs Lab Necessary for Melanoma; Local Recurrence After Mohs Surgery; Indications for MMS; Advantages of Mohs Surgery; Detecting Melanoma Upstaging Prior to Reconstruction; Mohs Excision with Clear Histologic Margins Prior to Reconstrution
Chapter 4: Role of Dermoscopy Introduction; Dermoscopy Technique; Anatomic Considerations of Lentigo Maligna Melanoma; Dermoscopic Features of LM/LMM; Progression Model of LMM; LM/LMM on Non-facial Skin; Dermoscopic Differential Diagnosis; Management of LM/LMM; Conclusion; References; Chapter 5: Pathologic Diagnosis; Introduction; Current Nomenclature; History: Hutchinson's Melanotic Freckle and Circumscribed Precancerous Melanosis of Dubreuilh; Histologic Diagnosis; Obtaining a Biopsy Specimen; Histologic Features; Ancillary Diagnostic Test; Immunohistochemistry
Immediate Reconstruction After Clear Mohs Histologic Margins Mohs Surgery for Lentigo Maligna Melanoma: Controversies; Importance of Establishing a Standard Definition for a "Positive Margin" of Melanoma; Challenges for Widespread Use of Mohs Surgery for Melanoma; Conclusion; References; Chapter 8: Histologic Processing and Evaluation of Surgical Excision Specimens; Introduction; Standard Breadloaf; Technique; Advantages; Limitations; Margin Controlled Excision Techniques; Mohs Micrographic Surgery Using Frozen Sections; Technique; Advantages; Limitations
Molecular Tests Differential Diagnosis; Melanocytic Hyperplasia of Sun-Damaged Skin; Solar Lentigo; Pigmented Actinic Keratosis; Lichen Planus-Like Keratosis; Pigmented Squamous Cell Carcinoma In Situ; Junctional Melanocytic Nevus; Future Considerations; Summary; References; Part III: Surgical Management; Chapter 6: Staged Excision Techniques; Introduction; Staged Excision Techniques; Square Procedure and Associated Variations; Spaghetti Technique and Associated Variations; Slow Mohs; Staged Excision with Radial Vertical Sections and Variations; Mapped Serial Excision
Summary This book provides a comprehensive approach to the diagnosis and management of melanoma of the lentigo maligna subtype, specifically. Authors from multiple fields provide educational information along with importantly relevant, practical, and insightful details to improve the understanding and management approach to this type of melanoma. The chapters address each aspect of this melanoma ranging from clinical presentation, clinical and pathologic diagnosis, surgical management, nonsurgical options, and followup. There is frequent misunderstanding when diagnosing and managing this type of melanoma due to the clinical, pathologic, and surgical complexities detailed. Educational resources truly dedicated to this topic are lacking presently
Notes Includes index
Staged Excision with Rush Permanent Sections with En Face Sectioning
Print version record
Subject Melanoma -- Diagnosis.
Melanoma -- Treatment.
Melanoma -- diagnosis.
Form Electronic book
Author Busam, Klaus J.
Nehal, Kishwer S.
ISBN 3319437879 (electronic bk.)
9783319437873 (electronic bk.)