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E-book

Title Deoxynucleoside analogs in cancer therapy / edited by Godefridus J. Peters
Published Totowa, N.J. : Humana Press, ©2006

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Description 1 online resource (xiii, 476 pages) : illustrations
Series Cancer drug discovery and development
Cancer drug discovery and development.
Contents Nucleoside Transport Into Cells -- The Role of Deoxycytidine Kinase in DNA Synthesis and Nucleoside Analog Activation -- Deoxynucleoside Kinases and Their Potential Role in Deoxynucleoside Cytotoxicity -- Nucleotidases and Nucleoside Analog Cytotoxicity -- Pumping Out Drugs -- Cytosine Arabinoside -- Clofarabine -- L-Nucleosides as Chemotherapeutic Agents -- Troxacitabine (Troxatyl ™) -- 9-?-D-Arabinofuranosylguanine -- Gemcitabine -- Clinical Activity of Gemcitabine as a Single Agent and in Combination -- Nucleoside Radiosensitizers -- NONMEM Population Models of Cytosine Arabinoside and Fludarabine Phosphate in Pediatric Patients With Leukemia -- ThecycloSal-Nucleotide Delivery System -- Purine and Pyrimidine-Based Analogs and Suicide Gene Therapy -- 3?-Deoxy-3?-Fluorothymidine as a Tracer of Proliferation in Positron Emission Tomography
Summary Annotation Deoxynucleoside Analogs in Cancer Therapy discusses the classes of chemotherapeutic agents, and their analogs that are active against both common solid tumors and leukemias
Bibliography Includes bibliographical references and index
Subject Deoxyribonucleotides -- Therapeutic use
Antineoplastic agents.
Cancer -- Chemotherapy.
Antimitotic agents.
Deoxyribonucleotides -- therapeutic use
Antineoplastic Agents -- therapeutic use
Neoplasms -- drug therapy
Antineoplastic Agents
Antimitotic Agents
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Antineoplastic agents.
Cancer -- Chemotherapy.
Deoxyribonucleotides -- therapeutic use.
Antineoplastic Agents -- therapeutic use.
Neoplasms -- drug therapy.
Biomédecine.
Sciences de la vie.
Antimitotic agents
Antineoplastic agents
Cancer -- Chemotherapy
Form Electronic book
Author Peters, Godefridus Johannes, 1952-
LC no. 2005036304
ISBN 1588293270
9781588293275
9781597451482
1597451487