| Description |
xix, 403 pages : illustrations ; 24 cm |
| Series |
Human molecular genetics series |
|
Human molecular genetics series.
|
| Contents |
1. The importance of environmental mutagens in human carcinogenesis and germline mutation / S. Venitt and D. H. Phillips -- 2. Role of mutagenesis and mitogenesis in carcinogenesis / J. C. Barrett -- 3. Molecular mechanisms of mutagenesis and mutational spectra / B. W. Glickman, G. Kotturi, J. de Boer and W. Kusser -- 4. Inherited susceptibility to mutation / D. G. Harnden -- 5. Pharmacogenetic polymorphisms / G. Smith, C. A. D. Smith and C. R. Wolf -- 6. Mutagenicity tests in bacteria as indicators of carcinogenic potential in mammals / E. Zeiger -- 7. In vitro cytogenetics and aneuploidy / E. M. Parry and J. M. Parry -- 8. In vivo assays for mutagenicity / J. A. Heddle -- 7. In vivo germ cell mutagenesis assays / J. B. Bishop and K. L. Witt -- 10. The mouse spot test / R. Fahrig -- 11. Mammalian cell mutation assays / D. Clive -- 12. Assays for unscheduled DNA synthesis in vivo / J. C. Mirsalis |
|
13. Use of genetically engineered cells for genetic toxicology testing / C. L. Crespi -- 14. Fluorescence in situ hybridization: application to environmental mutagenesis / D. A. Eastmond and D. S. Rupa -- 15. Measuring genetic events in transgenic animals / R. Forster -- 16. The single cell gel/Comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells / R. R. Tice -- 17. Human monitoring for somatic mutation in humans / R. J. Albertini and J. P. O'Neill -- 18. Protein and DNA adducts as biomarkers of exposure to environmental mutagens / D. H. Phillips and P. B. Farmer |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Carcinogenesis.
|
|
Chemical mutagenesis.
|
|
Environmentally induced diseases.
|
|
Mutagenesis.
|
| Author |
Phillips, D. H. (David H.)
|
|
Venitt, S.
|
| LC no. |
96140584 |
| ISBN |
1872748198 |
|
