| Description |
1 online resource (435 pages) |
| Contents |
Cover; Half Title; Title Page; Copyright Page; Table of Contents; Preface; 1: Nanocrystals in Medical Applications; 1.1 Introduction; 1.2 Characteristics of Drug Nanocrystals; 1.2.1 Improved Dissolution Rate; 1.2.2 Increased Solubility; 1.2.3 Improved Mucoadhesion; 1.2.4 Possible Drug Candidates for Nanocrystallization; 1.2.5 Cell Interactions of Drug Nanocrystals; 1.3 Preparation of Drug Nanocrystals; 1.3.1 Top-Down Methods; 1.3.2 Bottom-Up Methods; 1.3.3 Combination Methods; 1.3.4 Comparison of Different Techniques; 1.3.5 Stabilizer; 1.3.6 Quality-by-Design Approach |
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1.3.7 Scaling Up and Scaling Down1.4 Applications of Drug Nanocrystals; 1.5 Conclusions; 2: Cyclodextrin-Based Nanosystems: Current Status and Future Prospects; 2.1 Introduction; 2.2 Historical Perspective of Cyclodextrins; 2.3 Chemistry and Properties of Cyclodextrins; 2.3.1 Natural Cyclodextrins; 2.3.2 Modified Cyclodextrins; 2.3.3 Amphiphilic Cyclodextrins; 2.3.3.1 Nonionic amphiphilic cyclodextrins; 2.3.3.2 Cationic amphiphilic cyclodextrins; 2.3.3.3 Anionic amphiphilic cyclodextrins; 2.4 Cyclodextrin-Based Nanosystems; 2.4.1 Cyclodextrin-Based Nanoparticles |
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2.4.2 Cyclodextrin-Based Nanosponges2.4.3 Cyclodextrin-Based Liposomes; 2.4.4 Cyclodextrin-Based Hydrogels; 2.4.5 Cyclodextrin-Based Nanofibers; 2.4.6 Cyclodextrin Molecular Imprints; 2.4.7 Cyclodextrin Polymers; 2.5 Future Perspectives; 3: Hydrogels as Intelligent Drug Delivery Systems; 3.1 Introduction; 3.2 Hydrogels; 3.2.1 PEGylated Hydrogels; 3.2.2 Glucose-Responsive Hydrogels; 3.2.3 pH-Responsive Hydrogels; 3.2.4 Thermosensitive Hydrogels; 3.3 Hydrogels for Controlled Release of Drugs and Proteins; 3.4 Other Applications of Hydrogels; 3.4.1 Magnetic Hydrogels as Drug Delivery Systems |
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3.5 Limitations for Hydrogel Administration3.6 Conclusions and Future Perspectives; 4: Ocular Drug Delivery Nanosystems: Recent Developments and Future Challenges; 4.1 Introduction; 4.2 Ocular Drug Delivery Nanosystems; 4.2.1 Dendrimers; 4.2.2 Liposomes; 4.2.3 Niosomes; 4.2.4 Nanoparticles; 4.2.4.1 Solid lipid nanoparticles and nanostructured lipid carriers; 4.2.4.2 Polymeric nanoparticles; 4.2.4.3 Polymeric nanocapsules; 4.2.4.4 Polymeric micelles; 4.2.4.5 Inorganic gold and silver nanoparticles; 4.2.5 Nanosuspensions; 4.2.6 Nanogels; 4.2.7 Lipid-based liquid crystals (cubosomes, hexasomes) |
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4.2.8 Microemulsions4.2.9 Nanoemulsions; 4.2.10 Quantum Dots; 4.2.11 Contact Lenses; 4.2.12 Proteins and Peptides; 4.3 Future Challenges and Perspectives; 5: Dendrimers as a Candidate for Microbicide in Prevention of HIV-1 lnfection in Women: Steps toward Their Clinical Evaluation; 5.1 Introduction; 5.2 Dendritic Structures: Dendrimers as New Tools in HIV Microbicide Strategies; 5.2.1 Synthesis; 5.2.1.1 Polyanionic carbosilane dendrimers; 5.2.2 Characterization of Dendrimers; 5.2.3 Nomenclature and Types of Dendrimers; 5.2.4 Anionic and Cationic Dendrimers: Biological Applications |
| Notes |
5.3 The Human Immunodeficiency Virus Type I |
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Print version record |
| Subject |
Drug delivery systems.
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Drug Delivery Systems
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Drug delivery systems
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| Form |
Electronic book
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| Author |
Demetzos, Costas
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Pispas, Stergios
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| ISBN |
9780429955228 |
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0429955227 |
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9780429955211 |
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0429955219 |
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