| Description |
1 online resource (381 p.) |
| Contents |
Cover -- Title Page -- Copyright -- Contents -- Preface -- Chapter 1 Extracellular Matrix Hydrogels from Decellularized Tissues for Biological and Biomedical Applications -- 1.1 Introduction to Hydrogels -- 1.1.1 Definition and Use of Hydrogels in Biomedical Applications -- 1.1.2 Classification and Properties of Hydrogels -- 1.1.2.1 Synthetic Hydrogels -- 1.1.2.2 Natural Hydrogels -- 1.2 Key Features and Functions of the Extracellular Matrix in Homeostasis and Development -- 1.3 Extracellular Matrix-Based Hydrogels Derived from Decellularization of Organs -- 1.3.1 Production of ECM Hydrogels |
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1.3.2 Characterization of ECM Hydrogels -- 1.3.3 Pancreatic ECM-Derived Hydrogels -- 1.3.4 ECM Hydrogels Derived from Liver -- 1.3.5 Lung ECM Hydrogels -- 1.3.6 Hydrogels Derived from Decellularized Colon -- 1.3.7 ECM-Derived Hydrogels from Small Intestine -- 1.3.8 Cellular Responses to ECM Hydrogels -- 1.4 Commercially Available Products -- References -- Chapter 2 Collagen-Based Systems to Mimic the Extracellular Environment -- 2.1 Cells in Tissues -- 2.2 Collagen in Tissues -- 2.2.1 Structure of Collagen -- 2.2.2 Collagen Sources -- 2.3 Controlling Collagen Architecture |
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2.3.1 Direction: Collagen Orientation -- 2.3.2 Diameter: Collagen Fibril Diameter -- 2.3.3 Density: Fibril Packing and Cross-Linking -- 2.4 Engineering Collagen Scaffolds -- 2.4.1 Collagen Cross-Linking -- 2.4.2 Diffusion of Nutrients and Oxygen Through Collagen Scaffolds -- 2.4.3 Proliferation of Cells in 3D -- 2.4.4 Mechanical Stimulation and Bioreactors -- 2.4.5 Growth Factors -- 2.4.6 Drug-Loaded Scaffolds -- 2.5 Conclusions -- References -- Chapter 3 Designing Elastin-Like Recombinamers for Therapeutic and Regenerative Purposes -- 3.1 Introduction |
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3.2 ELR-Based Hydrogels in Tissue Engineering -- 3.2.1 Hydrogels in Musculoskeletal Tissue Regeneration -- 3.2.2 Hydrogels in Cardiovascular Tissue Regeneration -- 3.2.3 Hydrogels in Skin Tissue Regeneration -- 3.2.4 Hydrogels in Neural Tissue Regeneration -- 3.3 ELR-Based Hydrogels for Drug Delivery -- 3.3.1 Physically Cross-Linked Hydrogels -- 3.3.2 Chemically Cross-Linked Hydrogels -- 3.4 Future Remarks -- References -- Chapter 4 Enzyme-Assisted Hydrogel Formation for Tissue Engineering Applications -- 4.1 Introduction -- 4.2 Enzymatically Cross-Linked Hydrogels -- 4.2.1 Oxidoreductases |
| Notes |
Description based upon print version of record |
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5.2.1 Hydrophobic Aromatic Amino Acids |
| Form |
Electronic book
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| Author |
Pashkuleva, Iva
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Reis, Rui L
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| ISBN |
9783527825837 |
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3527825835 |
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