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Title Obesity and cancer / Tobias Pischon, Katharina Nimptsch, editors
Published Cham, Switzerland : Springer, 2016
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Description 1 online resource
Series Recent results in cancer research, 0080-0015 ; volume 208
Recent results in cancer research ; 208
Contents Preface; Contents; 1 Obesity and Risk of Cancer: An Introductory Overview; Abstract; 1 Introduction; 2 Definition and Assessment of Obesity; 3 Obesity and Cancer-Weighing the Evidence: A Historical Perspective; 3.1 Colorectal Cancer; 3.2 Breast Cancer; 3.3 Esophageal Cancer; 3.4 Kidney Cancer; 3.5 Pancreatic Cancer; 3.6 Endometrial Cancer; 3.7 Liver Cancer; 3.8 Prostate Cancer; 3.9 Ovarian Cancer; 3.10 Gallbladder Cancer; 4 Potential Mechanisms and Pathways for the Association of Obesity with Cancer Risk; 5 Burden of Cancer Attributable to Obesity on a Population Level; 6 Conclusions
3.1 General Obesity and Mortality in Colorectal Cancer Patients3.2 Abdominal Obesity and Mortality in Colorectal Cancer Patients; 3.3 Obesity and Treatment Outcomes in Colorectal Cancer Patients; 3.4 Summary and Recommendation on Weight Management in Colorectal Cancer Patients; 4 Weight Change in Adulthood and Risk of Colorectal Cancer; 4.1 Weight Gain and Colorectal Cancer Risk; 4.2 Weight Loss and Colorectal Cancer Risk; 4.3 Summary on the Effects of Weight Change on Colorectal Cancer Risk; 5 Relations of Childhood and Adolescent Obesity to Risks of Colorectal Cancer and Colorectal Adenoma
6 Potential Biological Mechanisms Linking Obesity to Colorectal Cancer6.1 Insulin Resistance, Hyperinsulinemia and Insulin-like Growth Factor; 6.2 Chronic Inflammation; 6.3 Hypoadiponectinemia and Hyperleptinemia; 6.4 Sex Hormones; 6.5 Summary of Potential Biological Mechanisms; 7 Summary and Future Research; References; 3 Obesity and Breast Cancer; Abstract; 1 Introduction; 2 Body Size Across the Life Course and Breast Cancer Risk; 2.1 Childhood Body Size; 2.2 General Adiposity in Adulthood and Breast Cancer; 2.2.1 BMI and Premenopausal Breast Cancer Risk
2.2.2 Premenopausal BMI and Postmenopausal Breast Cancer Risk2.2.3 Postmenopausal BMI and Breast Cancer Risk; 3 BMI and Breast Cancer-Specific Survival; 4 Weight Changes; 4.1 Weight Gain and Risk of Premenopausal Breast Cancer; 4.2 Weight Gain and Postmenopausal Breast Cancer Risk; 4.3 Weight Loss and Breast Cancer Risk; 4.4 Weight Change and Breast Cancer-Specific Survival; 5 Visceral Adiposity: Waist Circumference/Waist-Hip Ratio; 5.1 WC/WHR and Risk of Premenopausal Breast Cancer; 5.2 WC/WHR and Risk of Postmenopausal Breast Cancer; 5.3 WC and WHR and Breast Cancer-Specific Survival
Summary This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians
Bibliography Includes bibliographical references
Subject Cancer -- Risk factors.
Neoplasms -- etiology.
Obesity -- complications.
Form Electronic book
Author Pischon, Tobias, editor
Nimptsch, Katharina, editor
ISBN 9783319425429 (electronic bk.)
3319425420 (electronic bk.)