| Description |
1 online resource |
| Contents |
Cover; Title Page; Copyright Page; Contents; List of Contributors; Preface; Part One -- Chirality in Nature; Chapter 1 -- Chiral Asymmetry in Nature; 1.1 -- Introduction; 1.2 -- Chirality: Terminology and Quantification Issues; 1.2.1 -- Cahn-Ingold-Prelog classification of chiral molecules; 1.2.2 -- Optical rotation; 1.2.3 -- Enantiomeric excess; 1.2.4 -- Crystal enantiomeric excess; 1.2.5 -- Chirality measures; 1.3 -- Chiral Asymmetry in Nature; 1.3.1 -- Asymmetry in nuclear processes; 1.3.2 -- Asymmetry in atoms; 1.3.3 -- Asymmetry in molecules; 1.3.4 -- Biomolecular asymmetry |
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1.3.5 -- Morphological asymmetry1.3.6 -- Astrophysical asymmetries; 1.4 -- Theory of Spontaneous Chiral Symmetry Breaking; 1.5 -- Sensitivity of Chiral Symmetry Breaking Transitions to Asymmetric Interactions; 1.6 -- Examples of Spontaneous Chiral Symmetry Breaking; 1.7 -- Concluding Remarks; Acknowledgments; References; Chapter 2 -- Remote Sensing of Homochirality: A Proxy for the Detection of Extraterrestrial Life; 2.1 -- Introduction; 2.2 -- Homochirality; 2.2.1 -- The homochirality of life; 2.2.2 -- The origin of homochirality; 2.2.2.1 -- The initial imbalance |
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2.2.2.2 -- The amplification of the enantiomeric excess2.3 -- Chemical and biological mechanisms for creating circular spectropolarimetric signals; 2.3.1 -- The discovery of chirality and its relation to the polarization of light; 2.3.2 -- Optical rotatory dispersion, electronic circular dichroism, and circular polarization; 2.3.3 -- Electronic transitions and rotational strength; 2.3.4 -- Exciton coupling; 2.3.5 -- Large aggregates (PSI-type); 2.4 -- Considerations for the remote sensing of homochirality in our solar system and beyond; 2.4.1 -- Wavelength considerations; 2.4.2 -- In situ observations |
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2.4.3 -- Solar system observations (remote)2.4.4 -- Exoplanet observations; 2.5 -- Instrumentation; 2.5.1 -- Polarization measurement approaches; 2.5.1.1 -- Terminology: polarimetric sensitivity and accuracy; 2.5.1.2 -- Temporal modulation; 2.5.1.3 -- Snapshot modulation; 2.5.2 -- Mitigating linear polarization cross-talk; 2.5.3 -- Current and future instrument concepts; 2.6 -- Conclusion and outlook; References; Part Two -- Spectroscopic Methods and Analyses; Chapter 3 -- Light Polarization and Signal Processing in Chiroptical Instrumentation; 3.1 -- Introduction; Part A-The polarization of light |
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3.2 -- Light as a wave3.3 -- Types of polarized light; 3.3.1 -- Linearly polarized light; 3.3.2 -- Circularly polarized light; 3.3.3 -- Elliptically polarized light; 3.4 -- Production of linearly polarized light; 3.4.1 -- Polarization by scattering; 3.4.2 -- Polarization by reflection and refraction; 3.4.3 -- Polarization by birefringence; 3.4.4 -- Polarization by wire grids; 3.4.5 -- Polarization by dichroism; 3.5 -- Production of circularly polarized light; 3.6 -- Production of elliptically polarized light; 3.7 -- Photoelastic modulators; Part B-Signal handling; 3.8 -- Noise in electrical circuits |
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3.8.1 -- White noise |
| Summary |
Annotation 'Chiral Analysis' covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers |
| Notes |
Includes index |
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Online resource; title from PDF title page (ScienceDirect, viewed June 6, 2018) |
| Subject |
Chirality.
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Enantioselective catalysis.
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SCIENCE -- Chemistry -- Organic.
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Chirality
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Enantioselective catalysis
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| Form |
Electronic book
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| Author |
Polavarapu, Prasad L., editor.
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| ISBN |
9780444640284 |
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0444640282 |
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