| Description |
1 online resource (xi, 236 pages) : illustrations (some color) |
| Series |
Oxidative stress in applied basic research and clinical practice |
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Oxidative stress in applied basic research and clinical practice.
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| Contents |
880-02 Oxidative stress: impact in neuroscience research -- Oxidative stress and Alzheimer's disease -- Inflammation and Oxidation: a link in Alzheimer disease pathogenesis -- GAPDH: -amyloid mediated iron accumulation in Alzheimer's disease -- A in mitochondria: one piece in the Alzheimer's disease puzzle -- The role of the plasma membrane redox system in the pathognesis of Alzheimer's disease -- Metal dysfunction in Alzheimer's disease -- Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer's Disease -- Cholesterol metabolism and oxidative stress in Alzheimer's disease -- Brain hypometabolism, oxidative stress, maternal transmission and risk of late-onset Alzheimer's disease -- Stress and HPA axis dysfunction in Alzheimer's disease -- Diabetes mellitus and its impact on sporadic Alzheimer's disease -- Peripheral biomarkers of oxidative tress in Alzheimer's disease -- Nutrition lifestyle and oxidative stress: prevention in Alzheimer's disease -- Are antioxidants food and nutrients useful in preventing cognitive decline?.- Antioxidant clinical trials in Mild Cognitive Impairment and Alzheimer's disease |
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880-02/(S Part I: Hypotheses. Oxidative Stress: Impact in Neuroscience Research / Helmut Sies(hon) -- Oxidative Stress and Alzheimer's Disease / Rudy J. Castellani, Bei-Xu Li, Amna Farshori and Georgy Perry -- Inflammation and Oxidation: A Link in Alzheimer's Disease Pathogenesis / Kenneth Hensley -- GAPDH: β-Amyloid Mediated Iron Accumulation in Alzheimer's Disease: A New Paradigm for Oxidative Stress Induction in Neurodegenerative Disorders / Michael A. Sirover -- Aβ in Mitochondria--One Piece in the Alzheimer's Disease Puzzle / Maria Ankarcrona -- The Role of the Plasma Membrane Redox System in the Pathogenesis of Alzheimer's Disease / Sara M. Hancock, David I. Finkelstein and Ashley I. Bush -- Part II: Mechanisms. Metal Dysfunction in Alzheimer's Disease / Rosanna Squitti, Mariacristina Siotto and Carlo Salustri -- Brain Oxidative Stress in the Pathogenesis and Progression of Alzheimer's Disease / Rukhsana Sultana, Aaron M. Swomley and D. Allan Butterfield -- Cholesterol Metabolism and Oxidative Stress in Alzheimer's Disease / Luigi Iuliano and Valerio Leoni -- Brain Hypometabolism, Oxidative Stress, Maternal Transmission, and Risk of Late-Onset Alzheimer's Disease / Lisa Mosconi, John Murray, Pauline McHugh and Mony de Leon -- Stress and HPA Axis Dysfunction in Alzheimer's Disease / Yash B. Joshi and Domenico Praticò -- Part III: Clinics. Diabetes Mellitus and Its Impact on Sporadic Alzheimer's Disease / Weili Xu -- Peripheral Biomarkers of Oxidative Stress in Alzheimer's Disease / Fabio Di Domenico and Marzia Perluigi -- Nutrition, Lifestyle and Oxidative Stress: Prevention of Alzheimer's Disease / M. Cristina Polidori and Ludger Pientka -- Are Antioxidant Food and Nutrients Useful in Preventing Cognitive Decline? / Luc Letenneur, Catherine Feart, Pascale Barberger-Gateau -- Antioxidant Clinical Trials in Mild Cognitive Impairment and Alzheimer's Disease / Patrizia Mecocci, M. Cristina Polidori and Domenico Praticó |
| Summary |
This volume systematically reviews the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as oxidative stress, in the pathology of Alzheimer's disease. It describes the most current diagnostic tools, laboratory methods and technology, and suggests ways of prevention and treatment to emphasize the concept of the bench-to-bedside approach. Studies on Alzheimer's Disease provides thorough coverage of emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents, and several more relevant aspects. In addition, this book promotes the concept of using biomarkers representative of oxidative stress reactions and free-radical damage, as well as describing the effects of antioxidants in treating disease in clinical trials. This content is invaluable to both researchers studying the development of and clinicians treating patients with a diagnosis of Alzheimer's Disease |
| Notes |
Includes index |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed September 24, 2013) |
| Subject |
Alzheimer's disease.
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Alzheimer's disease -- Diagnosis
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Alzheimer Disease -- diagnosis
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Alzheimer Disease
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Alzheimer's disease
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Alzheimer's disease -- Diagnosis
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| Form |
Electronic book
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| Author |
Praticò, Domenico, editor
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Mecocci, Patrizia, editor
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| ISBN |
9781627035989 |
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1627035982 |
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1627035974 |
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9781627035972 |
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