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Author Pyle, Anna Marie, (Howard Hughes Medical Institute, Yale University, USA), speaker

Title Self-splicing intron RNAs : ribozymes, parasites and agents of genomic change / Anna Marie Pyle
Published London : Henry Stewart Talks, 2007
Online access available from:
HSTalks Biomedical & Life Sciences Collection    View Resource Record  

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Description 1 online resource (1 streaming video file (60 min.) : color, sound)
Series From DNA to proteins : the multiple levels of regulation, 2056-452X
Henry Stewart talks. Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation
Contents Contents: Different classes of introns -- Autocatalytic group I and group II introns -- Discovery of self-splicing -- Converting a self-splicing RNA into a multiple-turnover enzyme -- The "tetrahymena ribozyme" and discovery of RNA catalysis -- New insights into molecular recognition of RNA -- Group I intron structure and catalytic mechanism -- Group I intron applications -- Group II introns and the big picture -- Discovery of self-splicing by group II introns -- Chemical mechanism of group II intron reactions -- Catalytic engines for driving eukaryotic evolution -- Explaining specificity of group II ribozymes -- Group II intron ribozymes as model systems for RNA folding -- Group II ribozymes as model systems for RNA tertiary structure -- Nucleotide analog interference mapping -- Current map of important atoms -- Nucleotide analog interference suppression -- Lambda-lambda interaction -- 3D model of ai5gamma intron -- Group II introns as tools and therapeutics
Notes Animated audio-visual presentation with synchronized narration
Title from title frames
Mode of access: World Wide Web
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
Subject Introns.
Protein-protein interactions.
RNA splicing.
Evolution, Molecular.
Introns -- genetics.
Introns -- physiology.
RNA Splicing.
RNA -- chemistry.
RNA -- metabolism.
RNA, Catalytic.
Spliceosomes -- metabolism.
Genre/Form Video recordings.
Form Streaming video