Limit search to available items
Book Cover
E-book

Title Epidemiological and molecular aspects on cholera / T. Ramamurthy, S.K. Bhattacharya, editors
Published New York : Springer, [2011]
©2011
Online access available from:
Springer eBooks    View Resource Record  

Copies

Description 1 online resource (xi, 367 pages) : illustrations (some color)
Series Infectious disease
Infectious disease (Totowa, N.J.)
Contents Asiatic cholera: mole hills and mountains -- Endemic and epidemic cholera in Africa -- Phenotypic and molecular characteristics of epidemic and non-epidemic vibrio cholerae strains isolated in Russia and certain countries of Commonwealth of Independent States (CIS) -- The re-emergence of cholera in the Americas -- The evolution of vibrio cholerae as a pathogen -- Molecular epidemiology of toxigenic vibrio cholerae -- Diversity and genetic basis of polysaccharide biosynthesis in vibrio cholerae -- Significance of the SXT/R391 family of integrating conjugative elements in vibrio cholerae -- Small molecule signaling systems in vibrio cholerae -- Vibrio cholerae flagellar synthesis and virulence -- Filamentous phages of vibrio cholerae O1 and O139 -- Pathogenic potential of non-O1, non-O139 vibrio cholerae -- Proteases produced by vibrio cholerae and other pathogenic vibrios: pathogenic roles and expression -- Toxins of vibrio cholerae and their role in inflammation, pathogenesis, and immunomodulation -- Vibrio cholerae hemolysin: an enigmatic pore-forming toxin -- Integrin-mediated antimicrobial resistance in vibrio cholerae -- Aquatic realm and cholera -- Management of cholera
Summary Though cholera is an ancient disease, its perennial occurrence in several parts of the world has attracted many researches to find ways and means to combat the disease. The prevailing seventh pandemic cholera is dominating since 1961, but the dimension of the disease has taken several silhouettes, as the genetic structure and functions of the Vibrio cholerae has changed to a great extent. Several recent studies have shown that transformation of the pathogen at the molecular level has ameliorated several cholera outbreaks and epidemics of with successive new clones of V. cholerae. This comprehensive compilation, written by eminent international researchers reviews the epidemiology of cholera in Africa, Asia, Russia and Latin Americas. The other chapters contributed by acclaimed authors cover various aspects on evolution, polysaccaharide biosynthesis, SXT element, integrons, small molecule signalling systems, flagellar synthesis, filamentous phages, pathogenic role of proteases and hemolysin, and other putative virulence factors. In addition, ecology of V. cholerae and management of cholera were also discussed in detail. This book will be good source of information to all researchers with interests in infectious diseases, microbiology and molecular biology
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Cholera -- Epidemiology.
Cholera -- Molecular aspects.
Cholera -- epidemiology.
Cholera -- pathology.
Form Electronic book
Author Ramamurthy, T., 1953-
Bhattacharya, S. K.
LC no. 2010936274
ISBN 9781603272650 (electronic bk.)
1603272658 (electronic bk.)
(hbk.)
(hbk.)