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Uniform Title Clinical and translational science (Robertson)
Title Clinical and translational science : principles of human research / edited by David Robertson, Gordon H. Williams
Edition Second edition
Published London, United Kingdom : Academic Press is an imprint of Elsevier, [2017]
©2017
Online access available from:
ClinicalKey e-books    View Resource Record  
ScienceDirect eBooks    View Resource Record  
ScienceDirect eBooks    View Resource Record  

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Description 1 online resource (xx, 763 pages) : illustrations (some color)
Contents Introduction to clinical research -- Patient-oriented research -- Clinical trials -- Introduction to epidemiology -- The patient-centered outcomes research institute : current approach to funding clinical research and future directions -- Health-care technology assessment (HTA) -- Health services research : translating discovery and research into practice and policy -- Measurement of biological materials -- Imaging tools in clinical research : focus on imaging technologies -- Imaging tools in human research : focus on image-guided intervention -- Nanotechnology in clinical and translational research -- The use of questionnaires and surveys -- Information technology -- Principles of biostatistics -- Good clinical practice and good laboratory practice -- Introduction to human genetics -- Epidemiologic and population genetic studies -- Pharmacogenetics of drug metabolism -- Statistical techniques for genetic analysis -- Introduction to clinical pharmacology -- Adverse drug events -- Translating science to the bedside : the innovation pipeline -- Regulatory environment -- Ethical issues in translational research and clinical investigation -- Clinical research in the public eye -- Research in special populations : acute illnesses; critical care; and surgical patients -- Research in the emergency care environment -- Psychiatric disorders -- Research in special populations : geriatrics -- Clinical research in neurology -- Research in pediatrics -- Cancer as a paradigm for translational and clinical biomedical research -- Maintaining an emphasis on rare diseases with research initiatives and resources at the national center for advancing translational sciences -- Clinical and translational science infrastructure -- Education, training and career choices : training basic, clinical, and translational investigators -- A stepwise approach to a career in translational research -- Physician careers in the pharmaceutical industry -- Industry-sponsored clinical research in academia -- Governmental support of research -- The role of nonprofit, nongovernmental funding in support of biomedical research -- Modern drug discovery and development -- Pharmaceutical and biotechnology sector support of research -- The future of clinical research
Summary Clinical or translational science is the field of study devoted to investigating human health and disease, interventions and outcomes for the purposes of developing new treatment approaches, devices, and modalities to improve health. New molecular tools and diagnostic technologies based on clinical and translational research have lead to a better understanding of human disease and the application of new therapeutics for enhanced health. This book is designed as the most authoritative and modern resource for the broad range of investigators in various medical specialties taking on the challenge of clinical research. Prepared with an international perspective, this resource begins with experimental design and investigative tools to set the scene for readers. It then moves on to human genetics and pharmacology with a focus on statistics, epidemiology, genomic information, drug discovery and development, and clinical trials. Finally, it turns to legal, social, and ethical issues of clinical research concluding with a discussion of future prospects to provide readers with a comprehensive view of the this developing area of science
Notes Revised edition of: Clinical and translational science : principles of human research / edited by David Robertson, Gordon H. Williams. 1st ed. 2009
Bibliography Includes bibliographical references
Notes Online resource; title from electronic title page (ClinicalKey, viewed November 13, 2017)
Subject Humans.
Clinical Medicine.
Biomedical Research.
Genetic Research.
Clinical medicine -- Research.
Medicine, Experimental.
Form Electronic book
Author Robertson, David, 1947- editor
Williams, Gordon H., editor
ISBN 012802111X (electronic bk.)
9780128021118 (electronic bk.)
(paperback)
(paperback)
OTHER TI Preceded by: Clinical and translational science. 1st ed. 2009