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E-book

Title Cancer cell signaling : methods and protocols / edited by Martha Robles-Flores
Edition Second edition
Published New York, NY : Humana Press, 2014

Copies

Description 1 online resource (xi, 263 pages) : illustrations (some color)
Series Methods in Molecular Biology, 1064-3745 ; 1165
Methods in molecular biology (Clifton, N.J.) ; v. 1165. 1064-3745
Contents Use of Biguanides to Improve Response to Chemotherapy -- Evaluating Response to Metformin/Cisplatin Combination in Cancer Cells Via Metabolic Measurement and Clonogenic Survival -- Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy -- Interdependency Between Genetic and Epigenetic Regulatory Defects in Cancer -- Experimental Strategies to Manipulate the Cellular Levels of the Multifunctional Factor CTCF -- Use of Serum-Circulating miRNA Profiling for the Identification of Breast Cancer Biomarkers -- Prostate Cancer Detection Using a Non-Invasive Method for Quantifying mi RNAs -- DNA Methylation Analysis of Steroid Hormone Receptor Genes -- Control of Oncogenic mi RNA Function by Light-Activated mi RNA Antagomirs -- Methods for the Study of Long Non-Coding RNA in Cancer Cell Signaling -- Microvesicles as Mediators of Intercellular Communication in Cancer -- In Vivo Rat Model to Study Horizontal Tumor Progression -- An In Vivo Model to Study the Effects of Tumoral Soluble Factors on the Vascular Permeability in Mice -- Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis -- Zebrafish-Based Systems Pharmacology of Cancer Metastasis -- A Flow Cytometry-Based Assay for the Evaluation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Cancer Cells -- Gene Disruption Using Zinc Finger Nuclease Technology
Summary Cancer Cell Signaling: Methods and Protocols, Second Edition brings together the most recent advances in cancer cell signaling knowledge along with recent progress in the development of novel strategies and experimental cell models to study human cancer
Opening with a section on targeting cancer cell metabolism as an anticancer strategy, this detailed volume continues with parts describing protocols to study epigenetic control of cancer, protocols to study cancer metastasis, as well as two new techniques for cancer study. Written for the highly successful Methods in Molecular Biology series, chapters include introductions for their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls
Authoritative and timely, Cancer Cell Signaling: Methods and Protocols, Second Edition is an ideal guide to the techniques that will aid researchers in exploiting our current knowledge in order to make a profound impact in cancer prevention and treatment
Analysis biomedische wetenschappen
biomedicine
neoplasms
Medicine (General)
Geneeskunde (algemeen)
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed June 6, 2014)
Subject Cancer cells -- Laboratory manuals
Cellular signal transduction -- Laboratory manuals
Cancer -- Genetic aspects -- Laboratory manuals
Oncology.
Medical Oncology
Neoplasms -- physiopathology
Neoplasms
Neoplasms -- genetics
Signal Transduction -- physiology
Oncology
Cancer cells
Cancer -- Genetic aspects
Cellular signal transduction
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Robles-Flores, Martha, editor
ISBN 9781493908561
1493908561
1493908553
9781493908554